Results 31 to 40 of about 7,329 (254)
Hybrid Biological/Solid-State Nanopores [PDF]
Biomolecular translocation through the bacterial nanopore α hemolysin (αHL) has been suggested as a possible platform for next generation sequencing technology. In this method, a single protein pore is inserted in an otherwise impermeable lipid membrane and an applied electric field is used to drive charged biomolecules like DNA through it. Information
Hall, Adam +5 more
openaire +1 more source
Solid‐State Nanopore Array: Manufacturing and Applications
AbstractNanopore brings extraordinary properties for a variety of potential applications in various industrial sectors. Since manufacturing of solid‐state nanopore is first reported in 2001, solid‐state nanopore has become a hot topic in the recent years.
Hongshuai Liu +4 more
openaire +2 more sources
Fabrication and Applications of Solid-State Nanopores [PDF]
Nanopores fabricated from synthetic materials (solid-state nanopores), platforms for characterizing biological molecules, have been widely studied among researchers. Compared with biological nanopores, solid-state nanopores are mechanically robust and durable with a tunable pore size and geometry.
Qi Chen, Zewen Liu
openaire +3 more sources
Optofluidic devices with integrated solid-state nanopores [PDF]
This review (with 90 refs.) covers the state of the art in optofluidic devices with integrated solid-state nanopores for use in detection and sensing. Following an introduction into principles of optofluidics and solid-state nanopore technology, we discuss features of solid-state nanopore based assays using optofluidics. This includes the incorporation
Shuo, Liu +2 more
openaire +2 more sources
SINGLE-MOLECULE DETECTION AND MANIPULATION WITH BIOLOGICAL NANOPORES
Single-molecule electrophysiology techniques using protein-based or solid-state nanopores as nanoreactors were proven incredibly useful as platforms for sensing and biophysical characterisation of biological molecules (e.g., peptides, proteins), DNA ...
Irina SCHIOPU +5 more
doaj +1 more source
Surface coatings for solid-state nanopores
Nanopores enable the characterization of single biomolecules; to interrogate these molecules without artifacts from wall interactions, nanopore coatings are required.
Olivia M. Eggenberger +2 more
openaire +3 more sources
Digital immunoassay for biomarker concentration quantification using solid-state nanopores
The concentration of a biomarker in solution can be determined by counting single molecules. Here the authors report a digital immunoassay scheme with solid-state nanopore readout to quantify a target protein and use this to measure thyroid-stimulating ...
Liqun He +7 more
doaj +1 more source
Localized Nanopore Fabrication via Controlled Breakdown
Nanopore sensors provide a unique platform to detect individual nucleic acids, proteins, and other biomolecules without the need for fluorescent labeling or chemical modifications.
Cuifeng Ying +3 more
doaj +1 more source
DNA Translocations through Solid-State Plasmonic Nanopores [PDF]
Nanopores enable label-free detection and analysis of single biomolecules. Here, we investigate DNA translocations through a novel type of plasmonic nanopore based on a gold bowtie nanoantenna with a solid-state nanopore at the plasmonic hot spot.
Francesca Nicoli +4 more
openaire +2 more sources
Low-Area Four-Channel Controlled Dielectric Breakdown System Design for Point-of-Care Applications
In this study, we propose a low-area multi-channel controlled dielectric breakdown (CDB) system that simultaneously produces several nanopore sensors. Conventionally, solid-state nanopores are prepared by etching or drilling openings in a silicon nitride
Jonggi Hong +3 more
doaj +1 more source

