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Multicomponent solid dispersion a new generation of solid dispersion produced by spray-drying [PDF]
Journal of Drug Delivery Science and Technology, 2020 The term“multicomponent solid dispersion”is widely used in recent literature to describe solid formulationsconsisting of a special excipient's mixture and active moleculesfinely dispersed. However, this term has not yetbeen defined.
Laura Modica De Mohac +2 more
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Solid dispersion of ketoprofen in pellets
International Journal of Pharmaceutics, 2000The formulation of ternary solid dispersions of ketoprofen with Macrogol and kollagen hydrolizate derivative as carriers was elaborated on the basis of the results of the experiments in which different methods of solid dispersion preparation (melting, solvent method, different cooling), different concentrations of drug/carriers and molecular weight of ...
R, Jachowicz +4 more
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Solid dispersions of dihydroartemisinin in polyvinylpyrrolidone
Archives of Pharmacal Research, 2008In the present study the physicochemical characteristics of dihydroartemisinin, polyvinylpyrrolidone and their solid dispersions were evaluated at various proportions of drug and polyvinylpyrrolidone. These properties were investigated with X-ray diffraction, fourier transform infrared spectrophotometry, differential scanning calorimetry, equilibrium ...
Ansari, M., Sunderland, Bruce
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Characterization of nifedipine solid dispersions
International Journal of Pharmaceutics, 2002The sublingual administration of nifedipine (NIF) is currently used in clinical practice. The sublingual administration of NIF solid dispersions (SD), by using a suitable dispenser, appears an interesting approach in the treatment of moderate and severe hypertensive emergencies.
F. Cilurzo +3 more
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Evaluation of Solid Dispersions of Clofazimine
Drug Development and Industrial Pharmacy, 2002Clofazimine (CLF) was formulated with polyethylene glycol (PEG) and polyvinyl pyrrolidone (PVP) as a solid solid dispersion (SSD) to increase the aqueous solubility and dissolution rate of the drug. Different molecular weights of PEG (1500, 4000, 6000, and 9000 Da) and PVP (14,000 and 44,000 Da) were used in different drug:carrier weight ratios (1:1, 1:
Ajit S, Narang, Anand K, Srivastava
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Solid-state characterization of nifedipine solid dispersions
International Journal of Pharmaceutics, 2002The purpose of this study is to characterize the nature and solid-state properties of a solid dispersion system of nifedipine (33.3% w/w) in a polymer matrix consisting of Pluronic F68 (33.3% w/w) and Gelucire 50/13 (33.3% w/w). The nature of nifedipine dispersed in the matrix was studied by powder X-ray diffractometry (PXRD), differential scanning ...
Sudha R, Vippagunta +3 more
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International Journal of Drug Delivery Technology, 2014
Solid dispersions are one of the most promising strategies to improve the oral bioavailability of poorly water soluble drugs. By reducing drug particle size to the absolute minimum, and hence improving drug wettability, bioavailability may be significantly improved.
Sumant Saini, Yashwant .
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Solid dispersions are one of the most promising strategies to improve the oral bioavailability of poorly water soluble drugs. By reducing drug particle size to the absolute minimum, and hence improving drug wettability, bioavailability may be significantly improved.
Sumant Saini, Yashwant .
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Solid Dispersion: Recapitulation
Asian Journal of Pharmacy and Technology, 2020The approach to improve dissolution rate of hydrophobic drug and enhance the bioavailability, solid dispersion is one of the promising approaches in which dispersion of one or more drug substances (API) in a hydrophilic carrier at solid state is used.
Ankita G. Galam +3 more
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1991
We recently performed an extensive series of measurements of the bound electronic nonlinear refractive index n2 of a variety of solids at several wavelengths. We found that as the photon energy approached Eg (the band-gap energy), that n2 changed from positive to negative.
M Sheik-Bahae +4 more
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We recently performed an extensive series of measurements of the bound electronic nonlinear refractive index n2 of a variety of solids at several wavelengths. We found that as the photon energy approached Eg (the band-gap energy), that n2 changed from positive to negative.
M Sheik-Bahae +4 more
openaire +1 more source
Matrix Solid-Phase Dispersion (Mspd)
Journal of Biochemical and Biophysical Methods, 2000AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
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