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Certain rheologycal behaviour of paracetamol solid dispersion powders
Paracetamol powder (PAR) has poor compressibility, high cohesivity and is difficult to compress. We have prepared dispersions of PAR and 3-cyclodextrin (β-CD) in physical mixture form, kneaded solid dispersion and spray dried solid dispersion (the ratio ...
Tasić, Ljiljana, Pintye-Hódi, K
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Dielectric Dispersion in Solids
この論文は国立情報学研究所の電子図書館事業により電子化されました。
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Journal of Chromatography A, 2000
Matrix solid-phase dispersion (MSPD) is a patented process, first reported in 1989, for conducting simultaneous disruption and extraction of solid and semi-solid samples. MSPD permits complete fractionation of the sample matrix components as well as the ability to selectively elute a single compound or several classes of compounds from the same sample.
Steven A Barker
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Matrix solid-phase dispersion (MSPD) is a patented process, first reported in 1989, for conducting simultaneous disruption and extraction of solid and semi-solid samples. MSPD permits complete fractionation of the sample matrix components as well as the ability to selectively elute a single compound or several classes of compounds from the same sample.
Steven A Barker
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Solid dispersion is one of the most promising strategies to improve oral bioavailability of poorly soluble API. However, there are inconsistent dissolution performances of solid dispersion reported which entails further investigation.
Siok-Yee Chan
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Polymorphism in Solid Dispersions
Crystal Growth & Design, 2019Solid dispersions embed active pharmaceutical ingredients in polymeric carriers to improve their solubility. Three solid dispersion preparation techniques are typically employed: solvent evaporation, solvent-fusion, and fusion methods. Although these are also widely recommended as preparative methods for phase diagram determination, few examples exist ...
Karina Sanabria Ortiz +4 more
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Pharmaceutical Applications of Solid Dispersion Systems
Journal of Pharmaceutical Sciences, 1971W L, Chiou, S, Riegelman
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Fundamental aspects of solid dispersion technology for poorly soluble drugs
The solid dispersion has become an established solubilization technology for poorly water soluble drugs. Since a solid dispersion is basically a drug–polymer two-component system, the drug–polymer interaction is the determining factor in its design and ...
Yanbin Huang
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