Results 141 to 150 of about 778,801 (197)
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Polymorphism in Solid Dispersions
Crystal Growth & Design, 2019Solid dispersions embed active pharmaceutical ingredients in polymeric carriers to improve their solubility. Three solid dispersion preparation techniques are typically employed: solvent evaporation, solvent-fusion, and fusion methods. Although these are also widely recommended as preparative methods for phase diagram determination, few examples exist ...
Karina Sanabria Ortiz +4 more
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Solid-state characterization of nifedipine solid dispersions
International Journal of Pharmaceutics, 2002The purpose of this study is to characterize the nature and solid-state properties of a solid dispersion system of nifedipine (33.3% w/w) in a polymer matrix consisting of Pluronic F68 (33.3% w/w) and Gelucire 50/13 (33.3% w/w). The nature of nifedipine dispersed in the matrix was studied by powder X-ray diffractometry (PXRD), differential scanning ...
Sudha R, Vippagunta +3 more
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Solid Dispersion: Recapitulation
Asian Journal of Pharmacy and Technology, 2020The approach to improve dissolution rate of hydrophobic drug and enhance the bioavailability, solid dispersion is one of the promising approaches in which dispersion of one or more drug substances (API) in a hydrophilic carrier at solid state is used.
Ankita G. Galam +3 more
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Sustained-release amorphous solid dispersions
Drug Delivery and Translational Research, 2018The use of amorphous solid dispersions (ASD) to overcome poor drug solubility has gained interest in the pharmaceutical industry over the past decade. ASDs are challenging to formulate because they are thermodynamically unstable, and the dispersed drugs tend to recrystallize.
Julien, Maincent, Robert O, Williams
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Journal of Chromatography A, 2000
Matrix solid-phase dispersion (MSPD) is a patented process, first reported in 1989, for conducting simultaneous disruption and extraction of solid and semi-solid samples. MSPD permits complete fractionation of the sample matrix components as well as the ability to selectively elute a single compound or several classes of compounds from the same sample.
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Matrix solid-phase dispersion (MSPD) is a patented process, first reported in 1989, for conducting simultaneous disruption and extraction of solid and semi-solid samples. MSPD permits complete fractionation of the sample matrix components as well as the ability to selectively elute a single compound or several classes of compounds from the same sample.
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Matrix Solid-Phase Dispersion (Mspd)
Journal of Biochemical and Biophysical Methods, 2000AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
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Characterization of nifedipine solid dispersions
International Journal of Pharmaceutics, 2002The sublingual administration of nifedipine (NIF) is currently used in clinical practice. The sublingual administration of NIF solid dispersions (SD), by using a suitable dispenser, appears an interesting approach in the treatment of moderate and severe hypertensive emergencies.
F. Cilurzo +3 more
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Microwave generated solid dispersions containing Ibuprofen
International Journal of Pharmaceutics, 2008The purpose of this study was to apply the attractive technique of the microwaves irradiation (MW) for the preparation of solvent-free solid dispersions (SD). In particular, the microwave technology has been considered in order to prepare an enhanced release dosage form for the poorly soluble drug Ibuprofen (IBU), employing PVP/VA 60/40 (PVP/VA 64) and
MONEGHINI, MARIAROSA +3 more
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Dispersive solid phase microextraction
TrAC Trends in Analytical Chemistry, 2019Abstract Dispersive solid phase microextraction (DSPME) as a prepossessing solid phase microextraction (SPME) technique has been recently considered for the extraction, clean up, and preconcentration of different analytes in real samples. In this review, the advantages and disadvantages of DSPME against SPME are compared based on the practical ...
Mahdi Ghorbani +4 more
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