Results 111 to 120 of about 128,995 (308)

Properties of Intra-group Stars and Galaxies in Galaxy Groups: "Normal" versus "Fossil" Groups

, 2005
Cosmological LCDM simulations of 12 M_vir~10^14 Msun galaxy groups have been performed, invoking star formation, chemical evolution with non-instantaneous recycling, metallicity dependent radiative cooling, strong star-burst driven galactic super-winds ...
Antonuccio-Delogu, Arnaboldi, Binggeli, Binney, Borgani, Bryan, Castro-Rodrguez, D'Onghia, Da Rocha, Dressler, Dubinski, Durrell, Feldmeier, Feldmeier, Feldmeier, Feldmeier, Ferguson, Gal-Yam, Garilli, Girardi, Gladders, Gonzalez, Gonzalez, Helmi, Jesper Sommer-Larsen, Jones, Khosroshahi, Kormendy, Lia, Lia, Lin, Mackie, McNamara, Mihos, Murante, Napolitano, Oemler, Ponman, Romeo, Romeo, Sommer-Larsen, Springel, Tornatore, Ulmer, Valdarnini, White, Willman, Zaritsky   +47 more
core   +3 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Myth or Truth: The Glass Forming Ability Class III Drugs Will Always Form Single-Phase Homogenous Amorphous Solid Dispersion Formulations

Pharmaceutics, 2019
The physical stability of amorphous solid dispersions (ASD) of active pharmaceutical ingredients (APIs) of high glass forming ability (GFA class III) is generally expected to be high among the scientific community.
Piyush Panini, Massimiliano Rampazzo, Abhishek Singh, Filip Vanhoutte, Guy Van den Mooter   +4 more
doaj   +1 more source

solid dispersion

Citation: 'solid dispersion' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13917 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Klein tunneling and electron optics in Dirac-Weyl fermion systems with tilted energy dispersion

, 2018
The outstanding electronic properties of relativistic-like fermions have been extensively studied in solid state systems with isotropic linear dispersions such as graphene.
Charlier, Jean-Christophe, Nguyen, Viet Hung   +1 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

A direct numerical simulation method for complex modulus of particle dispersions

, 2010
We report an extension of the smoothed profile method (SPM)[Y. Nakayama, K. Kim, and R. Yamamoto, Eur. Phys. J. E {\bf 26}, 361(2008)], a direct numerical simulation method for calculating the complex modulus of the dispersion of particles, in which we ...
A. Malevanets, A. Shakib-Manesh, A.J.C. Ladd, H. Tanaka, H. Watanabe, H.H. Hu, H.M. Wyss, J. Kromkamp, J.F. Brady, J.J. Crassous, J.T. Padding, K. Kim, M. Fujita, M. Hecht, P.J. Atzberger, P.M. Kulkarmi, R. Yamamoto, R. Yamamoto, R.A. Lionberger, T. Araki, T. Iwashita, T. Iwashita, T. Iwashita, T. Iwashita, T. Kajishima, T. Kumagai, T. Shikata, T.G. Mason, V. Carrier, X. Lio, Y. Nakayama, Y. Nakayama   +31 more
core   +1 more source