Results 181 to 190 of about 263,841 (302)
PGXTEC) liquid technology is utilized to develop highly respirable yeast beta‐glucan (YBG) microparticles for the treatment of pulmonary fibrosis. Compared to conventionally processed spray‐dried YBG, PGXTEC‐YBG exhibits greatly improved aerodynamic properties, enhanced pro‐fibrotic macrophage uptake, and effective downregulation of pro‐fibrotic ...
Nate Dowdall +14 more
wiley +1 more source
Design rules are presented to control intestinal organoid polarity in fully synthetic hydrogels. The laminin‐derived IKVAV sequence is crucial to obtain correct intestinal organoid polarity. Increasing hydrogel dynamics further supports the growth of correctly polarized intestinal organoids, while a bulk level of stiffness (G’ ≈ 0.7 kPa) is crucial to ...
Laura Rijns +10 more
wiley +1 more source
A Reagent for the Convenient, Solid-Phase Synthesis of N-Terminal Peptide Hydroxylamines for Chemoselective Ligations [PDF]
Takeo Fukuzumi, Jeffrey W. Bode
openalex +1 more source
Propylphosphonic Anhydride (T3P®) as Coupling Reagent for Solid‐Phase Peptide Synthesis [PDF]
Othman Al Musaimi +4 more
openalex +1 more source
Norbornene Homopolymerization Limits Cell Spreading in Thiol–Ene Photoclick Hydrogels
Thiol–norbornene click reactions are often used in the development of cell‐permissive 3D hydrogels. However, ene–ene crosslinks in other thiol–ene systems are known to limit permissivity. This study demonstrates the negative effects of norbornene homopolymerization on 3D cell spreading and circumvents the issue by modulating polymer degree of ...
James L. Gentry, Steven R. Caliari
wiley +1 more source
Six stereoisomeric ruthenium‐peptide conjugates were synthesized and characterized, which showed high potential in photoactivated chemotherapy (PACT) and proximity protein labeling. Abstract Amino acid chirality is known to influence the biological properties of peptide‐containing prodrugs.
Liyan Zhang +7 more
wiley +1 more source
Synthesis of Some Analogs of Bradykinin Hormone Using Modified Solid Phase Peptide Synthesis and Microwave Technique (Part 1) [PDF]
M. A. Zewail +3 more
openalex +1 more source
Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery
This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo +3 more
wiley +1 more source

