Results 231 to 240 of about 263,841 (302)

Molecular Simulations of Polymer‐based Drug Nanocarriers: From Physical and Structural Properties to Controlled Release

Advanced Healthcare Materials, EarlyView.
Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao, Xin Jiang, Jinyu Li, Julien Nicolas, Tâp Ha‐Duong   +4 more
wiley   +1 more source

Living Materials Approach for In Situ Bio‐Polymers Production Using Bacillus Paralicheniformis in Microneedles

Advanced Healthcare Materials, EarlyView.
Dissolvable microneedle (MN) device containing Bacillus paralicheniformis. The polymeric matrix encapsulates and protects the bacteria, preserving their viability while enabling in situ production and release of γ‐polyglutamic acid. The bacteria are delivered into the skin via 500 µm‐long microneedles, and remain detectable on the skin 24 h post ...
Caroline Hali Alperovitz, Noa Ben David, Adi Gross, Boaz Mizrahi   +3 more
wiley   +1 more source

Covalent Epitope Decoration of Carbon Electrodes using Solid Phase Peptide Synthesis. [PDF]

Sci Rep, 2019
Candelaria L, Kalugin PN, Kowalski BM, Kalugin NG.   +3 more
europepmc   +1 more source

Improved Solid-Phase Peptide Synthesis of Wild-Type and Phosphorylated Phospholamban Using a Pseudoproline Dipeptide

, 2012
Shadi Abu‐Baker, Gary A. Lorigan
openalex   +2 more sources

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Highly efficient solid phase synthesis of large polypeptides by iterative ligations of bis(2-sulfanylethyl)amido (SEA) peptide segments

, 2013
Laurent Raibaut, Hélène Adihou, Rémi Desmet, Agnès F. Delmas, Vincent Aucagne, Oleg Melnyk   +5 more
openalex   +2 more sources

Structural Control of Photoconductivity in a Flexible Titanium‐Organic Framework

Advanced Materials, EarlyView.
The concept of flexibility is extended to titanium frameworks and use it to gain control over charge transport. MUV‐35 is a flexible doubly interpenetrated framework that can shrink spontaneously its volume by ≈40% to afford a photoconductive, porous state that is thermodynamically favored by non‐covalent interactions. Abstract The soft nature of Metal‐
Clara Chinchilla‐Garzón, Marta Galbiati, Alechania Misturini, Pol Gimeno‐Fonquernie, Neyvis Almora‐Barrios, Natalia M. Padial, Carlos Martí‐Gastaldo   +6 more
wiley   +1 more source

Supramolecular Chemistry in Metal–Organic Framework Materials

Advanced Materials, EarlyView.
This review highlights synergies between reticular chemistry and supramolecular chemistry. The role of supramolecular interactions in determining framework…guest interactions and attempts to understand dynamic behavior in metal–organic frameworks (MOFs), particularly emphasizing the development of crystal sponges, studying reactions in frameworks and ...
Eugenia Miguel‐Casañ, Georgia R. F. Orton, Danielle E. Schier, Neil R. Champness   +3 more
wiley   +1 more source

Scope and Limitations of γ-Valerolactone (GVL) as a Green Solvent to be Used with Base for Fmoc Removal in Solid Phase Peptide Synthesis. [PDF]

Molecules, 2019
Kumar A, Sharma A, de la Torre BG, Albericio F.   +3 more
europepmc   +1 more source

Solid/Solution Phase Peptide Synthesis of Novel Tris-PEGylated Reagents Using Aminocaproic Acid Spacers and Orthogonal Protecting Groups

, 2013
A. Felix, Alicia S. Miller
openalex   +1 more source