Results 61 to 70 of about 646,561 (358)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Research progress of solid-state pure culture equipment and technology [PDF]

open access: yesZhongguo niangzao
Solid-state pure culture is a biotechnology that simulates the natural fermentation environment. It uses solid matrix such as rice, bran, soybean meal as the growth medium for industrial microorganisms to ferment and produce by single microbial strain ...
TAI Yanxiang, YANG Wen, LIU Huipeng, HONG Housheng
doaj   +1 more source

Vermiculite as a new carrier for extracellular protease production by Aspergillus spp. under solid-state fermentation

open access: yesBiotechnology Reports, 2021
A new method has been developed to increase the productivity of aspergilli - producers of extracellular proteinases based on their cultivation on vermiculite under solid-state fermentation conditions.
Alexander A. Osmolovskiy   +4 more
doaj   +1 more source

Physicochemical Factors Affecting Microbiota Dynamics During Traditional Solid-State Fermentation of Chinese Strong-Flavor Baijiu

open access: yesFrontiers in Microbiology, 2020
Spontaneous solid-state fermentation (SSF) of Chinese Baijiu involves diverse microbes from Daqu and pit mud (PM). Given that the transfer of interphase microflora during the fermentation is a continuous and dynamic process, longitudinal studies are ...
Tong-wei Guan   +4 more
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Research Progress on Monitoring and Regulation of Closed Solid-State Fermentation Systems [PDF]

open access: yesShipin Kexue
A closed solid-state fermentation system refers to a system that automatically and intelligently completes solid-state fermentation under closed and controllable conditions to stabilize product quality, reduce labor intensity and improve intelligence ...
ZHANG Nan, CHENG Siyuan, YU Yongjian, DOU Shuaiwei, LIU Jiaxin, TANG Ruijun, ZHU Yuanyuan, YU Zhen
doaj   +1 more source

The effect of olive cake types on lipase production by isolated Rhizopus sp. and process statistical optimization [PDF]

open access: yes, 2013
The aim of this work was to study the production of extracellular lipase by solid-state fermentation with different olive cakes varieties including Mary, Shenghe and Yellow from isolated fungi using agro-industries waste such as rice straw, rice barn and
Gholam Khayati   +2 more
core  

Solid-State Fermentation as a Novel Paradigm for Organic Waste Valorization : a Review [PDF]

open access: yes, 2017
The abundance of organic solid waste throughout the world has become a common issue that needs complete management at every level. Also, the scarcity of fuel and the competition between food and substance as an alternative to a petroleum-based product ...
Ali   +44 more
core   +3 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Contribution of Debaryomyces hansenii to Microbial, Lipidome, and Flavor Properties of Sichuan Bacon

open access: yesFermentation
Debaryomyces hansenii has the potential to enhance the flavor profile of traditional fermented meat products. This study investigates the impact of the D. hansenii LY090 strain on the microbial community, lipidome, flavor profiles, and sensory properties
Song Wang   +5 more
doaj   +1 more source

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