Efficient activation of T cells by human monocyte-derived dendritic cells (HMDCs) pulsed with Coxiella burnetii outer membrane protein Com1 but not by HspB-pulsed HMDCs [PDF]
Background Coxiella burnetii is an obligate intracellular bacterium and the etiologic agent of Q fever; both coxiella outer membrane protein 1 (Com1) and heat shock protein B (HspB) are its major immunodominant antigens.
Ying Wang +4 more
core +2 more sources
Modulation of pro-inflammatory activation of monocytes and dendritic cells by aza-bis-phosphonate dendrimer as an experimental therapeutic agent [PDF]
INTRODUCTION: Our objective was to assess the capacity of dendrimer aza-bis-phosphonate (ABP) to modulate phenotype of monocytes (Mo) and monocytes derived dendritic cells (MoDC) activated in response to toll-like receptor 4 (TLR4) and interferon γ (IFN-
Alain Cantagrel +8 more
core +4 more sources
Effects of RANKL-Targeted Therapy in Immunity and Cancer. [PDF]
The role of the receptor activator of nuclear factor-κB ligand (RANKL)/RANK system is well characterized within bone, where RANKL/RANK signaling mediates osteoclastogenesis and bone resorption.
Cheng, Michael L, Fong, Lawrence
core +2 more sources
Rift Valley fever (RVF) is a mosquito-borne zoonosis of major concern for human and animal health, yet no licensed human vaccine exists. Here, we engineered a self-assembling nanoparticle vaccine candidate by genetically fusing the RVF virus glycoprotein
Margarida Q. Rodrigues +4 more
doaj +1 more source
Dendritikus sejt altípusok együttműködése fiziológiás és kóros állapotban = The interplay of dendritic cell subtypes in health and disease [PDF]
A dendritikus sejtek (DC) az immunfolyamatok fontos irányítói, melyek alapvető szerepet játszanak a központi és perifériás tolerancia és a gyulladásos folyamatok kiváltásában, fenntartásában és szabályozásában.
Benkő, Szilvia +9 more
core
Molecular signatures of maturing dendritic cells: implications for testing the quality of dendritic cell therapies [PDF]
Background Dendritic cells (DCs) are often produced by granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-4 (IL-4) stimulation of monocytes.
Ping Jin +31 more
core +2 more sources
A dendritic cell (DC)-based vaccine strategy could reduce the risk of recurrence and improve the survival of breast cancer patients. However, while therapy-induced apoptosis of hepatocellular and colorectal carcinoma cells can enhance maturation and ...
Jin Zheng +10 more
doaj +2 more sources
370 Soluble CD83 inhibits skin inflammation to chemical sensitizers [PDF]
P. Mihatsch +7 more
openaire +1 more source
Background: Dendritic cells (DCs) migrate from the periphery to the T cell zone of secondary lymphoid organs. Thus, activated DCs are specialized cells that obtain information from the periphery and transfer it to lymphoid organs.
Keykavos Gholami +4 more
doaj
Evaluation of the effect of GM-CSF blocking on the phenotype and function of human monocytes [PDF]
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a multipotent cytokine that prompts the proliferation of bone marrow-derived macrophages and granulocytes.
Esmaeil, Nafiseh +3 more
core +2 more sources

