Results 201 to 210 of about 134,028 (256)
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Serum interleukin-6 and interleukin-6 soluble receptor in Alzheimer's disease
Neuroscience Letters, 1998Serum levels of interleukin-6 (IL-6) and interleukin-6 soluble receptor (IL-6sR) were measured in 41 patients (23 female and 18 male, mean age 72.5 years) with Alzheimer's disease (AD) and in 32 controls (14 women and 18 men, mean age 69.2 years) using enzyme-linked immunosorbent assays (ELISA).
P, Angelis +4 more
exaly +3 more sources
Journal of Affective Disorders, 1995
Recently, it was found that major depression may be accompanied by significant changes in cell-mediated and humoral immunity. The purpose of this study was to investigate the plasma concentrations of interleukin (IL)-6, soluble IL-6 receptor (sIL-6R), sIL-2R and transferrin receptor (TfR) in patients with major depression in an acute phase of illness ...
Michael Maes, , Roger Desnyder
exaly +3 more sources
Recently, it was found that major depression may be accompanied by significant changes in cell-mediated and humoral immunity. The purpose of this study was to investigate the plasma concentrations of interleukin (IL)-6, soluble IL-6 receptor (sIL-6R), sIL-2R and transferrin receptor (TfR) in patients with major depression in an acute phase of illness ...
Michael Maes, , Roger Desnyder
exaly +3 more sources
The soluble interleukin‐6 receptor is generated by shedding
European Journal of Immunology, 1993AbstractThe ligand‐binding subunit (gp80) of the human interleukin‐6 receptor (IL‐6R) was transiently expressed in COS‐7 cells. The metabolically labeled protein was shown to be quantitatively released from the membrane within 20 h. We identified the protein released from the transfected COS‐7 cells after purification to homogeneity and N‐terminal ...
Mülberg, Jürgen +8 more
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Anti-Interleukin-6 and Soluble Interleukin-6 Receptor in Systemic Lupus Erythematosus
Lupus, 1994IL-6, soluble IL-6 receptor and IgG with anti-IL-6 activity were measured in the plasma of 14 lupus patients and 10 normal subjects. The capacity of peripheral blood mononuclear cells to spontaneously produce IL-6 in vitro was also measured. Our results indicate that IL-6 plasma levels in patient plasma as measured by ELISA were not different from ...
M, Evans, N I, Abdou
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Serum Interleukin-6, Soluble Interleukin-6 Receptor and Crohn’s Disease Activity
Digestive Diseases and Sciences, 2007The relationship between plasma interleukin-6 (IL-6) concentration and its soluble receptor in Crohn's disease (CD) is not well elucidated. Twenty healthy volunteers and 94 consecutive patients with CD (44 in relapse and 50 in remission) were studied. Plasma IL-6 concentrations in patients with active disease [80 +/- 9 pg/ml; mean +/- standard error of
Stéphane, Nancey +5 more
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Interleukin-6 and Soluble Interleukin-6 Receptor: Direct Stimulation of gp130 and Hematopoiesis
Blood, 1998T HE INTERLEUKIN-6 (IL-6) family of cytokines acts via receptor complexes that contain at least one subunit of the signal transducing protein gp130.[1][1] The family comprises IL-6, IL-11, ciliary neurotrophic factor (CNTF), cardiotrophin-1 (CT-1), leukemia inhibitory factor (LIF), and oncostatin ...
M, Peters, A M, Müller, S, Rose-John
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Serum Interleukin-6 Soluble Receptor in Relation to Interleukin-6 in Stroke Patients
Journal of Molecular Neuroscience, 2004Cerebral ischemia triggers interleukin-6 (IL-6) release into blood. IL-6 is a key mediator of acute phase reaction. Markers of acute phase reaction (C-reactive protein, fibrinogen, fever) have been linked to poor prognosis in stroke patients. Interleukin-6 soluble receptor (sIL-6R) can potentiate IL-6 pro-inflammatory activity.
Tomasz, Dziedzic +4 more
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Soluble Interleukin 6 Receptor is Biologically Active In Vivo
Cytokine, 1995A cancer cell transfection model was used to evaluate biological activity of soluble IL-6 receptor (sIL-6R) in vivo. B-78 melanoma cells were stably transfected with cDNAs encoding human IL-6, murine sIL-6R and human leukaemia inhibitory factor (LIF).
Mackiewicz, Andrzej +6 more
openaire +3 more sources