Results 71 to 80 of about 9,609 (148)
Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease
Portal Hypertension &Cirrhosis, Volume 5, Issue 2, Page 189-206, June 2026.MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang +5 more
wiley +1 more source
Hepatic Mitochondrial Renin-Angiotensin Systems
, 2015 Introduction: The circulating renin-angiotensin system (RAS) was originally described as a key endocrine regulator of intravascular homeostasis; however, the existence of a local (tissue) RAS has become increasingly reported in a variety of tissues ...
Skipworth, JRA
core
, 2013 The renin–angiotensin system (RAS) plays pivotal roles in homeostasis, but its abnormal activation has been proposed as a risk factor for several disorders including diabetes. Using animal models, we previously clarified the molecular mechanisms in which
Kanda, Atsuhiro, Ishida, Susumu
core +1 more source
Acta Physiologica, Volume 242, Issue 6, June 2026.ABSTRACT Aim Myocardial infarction (MI) is one of the leading causes of death worldwide. MI is associated with cardiac structural and functional alterations. Among these, cardiac fibrosis may be significantly influenced by mitochondrial dysfunction. We sought to evaluate whether the injection of functional mitochondria from healthy muscle could improve
María Cuesta‐Corral +13 more
wiley +1 more source
Clinical and Translational Science, Volume 19, Issue 6, June 2026.Overview of patient centric microsampling approach for monitoring respiratory biomarkers for treatment optimization. Image created in BioRender. Khan, A. (2026) https://BioRender.com/17jm5cs. ABSTRACT The clinical heterogeneity of respiratory disorders emphasizes the need for personalized approaches to prevention, diagnosis, and therapy.
Ahmar Khan +4 more
wiley +1 more source
Serum Soluble (Pro)renin Receptor Level as a Prognostic Factor in Patients Undergoing Maintenance Hemodialysis [PDF]
J Endocr Soc, 2021 Morimoto S, Amari Y, Suda C, Ichihara A.
europepmc +2 more sources
Prorenin receptor regulates more than the renin-angiotensin system
, 2012 The (pro)renin receptor (PRR) was initially believed to be a contributor to the pathogenesis of cardiovascular diseases via the amplification of renin- or prorenin-induced angiotensin (Ang) formation.
Binger, K.J. +2 more
core +1 more source
(Pro)renin receptor is associated with angiogenic activity in proliferative diabetic retinopathy. [PDF]
, 2012 AIMS/HYPOTHESIS: The renin-angiotensin system (RAS) potentially has a role in the development of end-organ damage, and tissue RAS activation has been suggested as a risk factor for diabetic retinopathy.
Ishida, S. +3 more
core +1 more source
Soluble (Pro)Renin Receptor Level in Patients with Severe Obesity Is Associated with Visceral Adiposity and Is Involved with Insulin Resistance and Renal Injury. [PDF]
Obes Facts, 2023 Yamaguchi T +12 more
europepmc +1 more source
Soluble (Pro)Renin Receptor as a Negative Regulator of NCC (Na+-Cl- Cotransporter) Activity. [PDF]
Hypertension, 2021 Xu C, Chen Y, Wang F, Xie S, Yang T.
europepmc +1 more source