Results 61 to 70 of about 9,609 (148)

Serum Soluble (Pro)Renin Receptor Levels in Maintenance Hemodialysis patients

open access: yes, 2020
博士(医学) 乙第3019号(主論文の要旨、要約、審査結果の要旨、本文),著者名:Yoshifumi AMARI・Satoshi MORIMOTO・Fumitaka NAKAJIMA・Takashi ANDO・Atsuhiro ICHIHARA, タイトル:Serum Soluble (Pro)Renin Receptor Levels in Maintenance Hemodialysis Patients,掲載誌:PloS one.(1932-6203),巻・頁・年:11巻 7号 p ...
甘利, 佳史
core  

Supplementary Materials for Mutagenesis of the Cleavage Site of (Pro)Renin Receptor Abrogates Aldosterone-salt-Induced Hypertension and Renal injury in Mice

open access: yes, 2022
   Soluble (pro)renin receptor (sPRR), the extracellular domain of (pro)renin receptor (PRR), is primarily generated by site-1 protease (S1P) and furin.
Tianxin Yang (13411827)   +5 more
core   +1 more source

A Network‐Based Approach to Understanding Key Signaling Pathways in Intervertebral Disc Biology

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
A literature‐based signaling network capturing the most relevant pathways in human nucleus pulposus cells was first constructed from curated biological evidence. The network was then translated into a system of ordinary differential equations to derive steady‐state solutions and define median baseline activity levels.
Sofia Tseranidou   +11 more
wiley   +1 more source

Forsythiaside A Alleviates Kidney Injury and Intestinal Epithelium Dysfunction in IgA Nephropathy by Inhibiting TLR4/NF‐κB Signaling

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 42, Issue 6, June 2026.
ABSTRACT IgA nephropathy (IgAN), the most common form of glomerulonephritis, is a major and growing public health issue. It results from intestinal barrier dysfunction that leads to mesangial deposition of pathogenic galactose‐deficient IgA1 (Gd‐IgA1) and renal inflammation.
Meng‐Si Li, Kai Liu
wiley   +1 more source

Fatty Acid Metabolism in Health and Cancer: From Fundamental Mechanisms to Therapeutic Application

open access: yesMedComm, Volume 7, Issue 6, June 2026.
The modulation of the TME by fatty acid metabolism primarily occurs through four key pathways: inflammation regulation, signal transduction, translation to TME, and oxidative stress. ABSTRACT Fatty acid metabolism (FAM) plays a vital role in maintaining health by supporting energy production, cellular structure, and signaling processes.
Na Hang   +12 more
wiley   +1 more source

The vascular renin-angiotensin-aldosterone system

open access: yes, 2001
PhDThe renin-angiotensin-aldosterone system (RAAS) is one of the major regulators of blood pressure. The actions and generation of RAAS components at the tissue level are less well appreciated.
Xiao, Fang
core  

Loss of Soluble (PRO)renin receptor attenuates kidney injury and fibrosis in unilateral ureteral obstruction

open access: yes, 2023
honors thesisCollege of ScienceChemistryNirupama RamkumarThe prorenin receptor (PRR) is a recently discovered component of the Renin-Angiotensin-Aldosterone System (RAAS) that is involved in the maintenance of kidney function and blood pressure. Cleavage
Gopinath, Dhruvan
core  

(Pro)renin Receptor Expression Increases throughout the Colorectal Adenoma—Adenocarcinoma Sequence and It Is Associated with Worse Colorectal Cancer Prognosis [PDF]

open access: yes, 2019
(Pro)renin receptor (PRR) is a protein that takes part in several signaling pathways such as Renin Angiotensin System and Wnt signalling. Its biological role has recently been related to cancer progression and in this study, we investigated its relevance
Gorka Larrinaga   +15 more
core   +2 more sources

Nutritional Composition and Potential Actions of Bioactive Compounds From Wild Laurus nobilis in the Management of Pulmonary Fibrosis‐Induced Cardiopathy in Rats

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 11, 15 June 2026.
ABSTRACT Wild Laurus nobilis fruits, a well‐known dietary plant, have been documented to alleviate cardiopathy associated with pulmonary fibrosis, but the underlying mechanisms remain largely unspecified. This current study aimed to investigate the potential therapeutic effects of wild L.
Saber Jedidi   +5 more
wiley   +1 more source

(Pro)Renin Receptor: A Novel Target for Hypertension, Kidney Disease, and Metabolic Syndrome

open access: yes, 2016
The enzyme renin plays a role in the development of hypertension (high blood pressure), cardiovascular disease, and kidney disease. Studies in mice and rats unexpectedly uncovered other biological activities of the receptor for renin and its precursor ...
Yang, T.
core  

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