Results 41 to 50 of about 9,609 (148)

Rewiring nutrition: Chemical insights into the physiological and microbiological roles of food's microconstituents

Food Biomacromolecules, EarlyView.
Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley   +1 more source

Unravelling soluble (pro)renin receptor-mediated endothelial dysfunction

European Journal of Pharmacology
Preeclampsia is characterized by maternal endothelial dysfunction and new-onset hypertension. Preeclamptic pregnancies have elevated levels of maternal soluble prorenin receptor (s(P)RR) and previous studies have shown that recombinant s(P)RR produces hypertension and vascular dysfunction. This study aimed to investigate the effects of PRO20, an s(P)RR
Lachlan G. Schofield, Juyi Zhao, Yu Wang, Sarah J. Delforce, Saije K. Endacott, Eugenie R. Lumbers, Dan Ma, Kirsty G. Pringle   +7 more
openaire   +2 more sources

Serum Soluble (Pro)Renin Receptor Levels in Maintenance Hemodialysis patients

, 2019
東京女子医科大学博士(医学)博士(医学) 乙第3019号(主論文の要旨、要約、審査結果の要旨、本文)，著者名:Yoshifumi AMARI・Satoshi MORIMOTO・Fumitaka NAKAJIMA・Takashi ANDO・Atsuhiro ICHIHARA, タイトル:Serum Soluble (Pro)Renin Receptor Levels in Maintenance Hemodialysis Patients，掲載誌:PloS one.(1932-6203)，巻・頁・年 ...
甘利, 佳史
openaire   +3 more sources

Correlations between plasma soluble (pro)renin receptor [s(P)RR] and clinical parameters in all the patients.

, 2016
Correlations between plasma soluble (pro)renin receptor [s(P)RR] and clinical parameters in all the patients.
Tomoyuki Fujikura (3167394), Takayuki Tsuji (3167385), Atsushi Otsuka (203611), Sayaka Ishigaki (3167388), Hiroshi Furuse (3167400), Naro Ohashi (168272), Akihiko Kato (798462), Takamasa Iwakura (798461), Seiichiro Ozono (3167397), Hideo Yasuda (710367), Shinsuke Isobe (3167391), Masafumi Ono (141379), Yasuo Ishii (210979), Takahisa Suzuki (162638)   +13 more
core   +1 more source

Food‐grade proteins, lipids, and fibers as potential tools to ameliorate cardiovascular disorders: A review

Food Biomacromolecules, EarlyView.
Abstract Cardiovascular diseases (CVDs) remain the leading cause of global mortality, necessitating effective preventive and adjunct therapeutic strategies beyond conventional pharmacological interventions. Although previous reviews have focused on individual nutrients or dietary patterns, this review provides a mechanism‐based, integrative perspective
Sridevi Shanmugam, Rukaiah Fatma Begum, Nirenjen Shanmugasundaram, Bhupendra Gopalbhai Prajapati, Suresh Ankul Singh, Pavithra Nagenthran, Sudarshan Singh, Kesarla Rajesh   +7 more
wiley   +1 more source

Association between soluble (Pro)renin receptor concentration in cord blood and small for gestational age birth: a cross-sectional study. [PDF]

PLoS One, 2013
ObjectiveThe (pro)renin receptor [(P)RR] has been recognized as a multifunctional receptor. The purpose of this study was to assess the association between plasma soluble (P)RR [s(P)RR] concentration in human cord blood (i.e., neonatal blood at birth ...
Watanabe N, Morimoto S, Fujiwara T, Suzuki T, Taniguchi K, Ando T, Kimura T, Sago H, Ichihara A.   +8 more
europepmc   +2 more sources

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor

, 2007
OBJECTIVE: Mannose 6-phosphate receptors (M6PR) bind both renin and prorenin, and such binding contributes to renin/prorenin clearance but not to angiotensin generation. Here, we evaluated the kinetics of renin/prorenin binding to the recently discovered
Burckle, C.A., Nguyen, G., Batenburg, W.W., Danser, A.H.J., Krop, M., Garrelds, I.M., de Bruin, R.J.A., Mueller, D.N., de Vries, R., Bader, M.   +9 more
core   +1 more source

TREM2+ macrophages accumulate in childhood IgA nephropathy and soluble TREM2 represents a reliable non‐invasive biomarker

Experimental Physiology, EarlyView.
Abstract IgA nephropathy (IgAN) is a common type of primary glomerulonephritis in children. The pathogenesis of childhood IgAN remains unclear, and there is a lack of effective non‐invasive biomarkers for this disease. Single‐cell RNA sequencing was performed in children with IgAN to delineate cellular and molecular compositions, and subcluster ...
Ling Yu, Xuan Gang, Jingjing Wang, Guoping Huang, Qiuyu Li, Weizhong Gu, Haidong Fu, Jianhua Mao   +7 more
wiley   +1 more source

Neuroprotective roles of klotho: Molecular pathways and therapeutic implications for cognitive health in neurological and psychiatric diseases

Experimental Physiology, EarlyView.
Abstract Klotho, a pleiotropic protein initially identified for its role in kidney function, has garnered significant attention for its neuroprotective properties in various neurodegenerative diseases. It regulates key processes, such as oxidative stress, neuroinflammation, synaptic plasticity and myelination, all crucial for maintaining neuronal ...
Amir Arsalan Ghahari, Leylinaz Safaeihavadaragh, Mehrdad Nourizadeh, Shaghayegh Davari, Saba Safaei, Farshad Zare, Safa Alkayyat, Erfan Kamali Far   +7 more
wiley   +1 more source