Results 81 to 90 of about 9,609 (148)

(Pro)renin receptor: Involvement in diabetic retinopathy and development of molecular targeted therapy

, 2018
The renin–angiotensin system (RAS), a crucial regulator of systemic blood pressure (circulatory RAS), plays distinct roles in pathological angiogenesis and inflammation in various organs (tissue RAS), such as diabetic microvascular complications.
Atsuhiro Kanda, Susumu Ishida
core   +1 more source

A Novel Single-Strand RNAi Therapeutic Agent Targeting the (Pro)renin Receptor Suppresses Ocular Inflammation

, 2017
The receptor-associated prorenin system (RAPS) refers to the pathogenic mechanism whereby prorenin binding to the (pro)renin receptor [(P)RR] dually activates the tissue renin-angiotensin system (RAS) and RAS-independent intracellular signaling.
Atsushi Shibata, Atsuhiro Kanda, Kousuke Noda, Kenichi Namba, Susumu Ishida, Erdal Tan Ishizuka, Hidekazu Toyofuku, Takahiro Matsumoto   +7 more
core   +1 more source

Envolvimento da angiotensina II nos eventos iniciais da sepse avaliado através de parâmetros hemodinâmicos e inflamatórios [PDF]

, 2009
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia.A sepse consiste em uma síndrome de resposta inflamatória sistêmica secundária à infecção. A angiotensina II além de
Pacheco, Letícia Kramer
core  

Role of (pro)renin receptor in albumin overload-induced nephropathy in rats

, 2018
Proteinuria is not only a common feature of chronic kidney diseases (CKD) but also an independent risk factor promoting CKD progression to end-stage renal failure.
Jiahui Su, Mokan Deng, Chuanming Xu, Jing-Song Ou, Li Zhou, Lei Wang, Hui Fang, Tianxin Yang, Weidong Wang, Linlin Zhang, Aihua Lu   +10 more
core   +1 more source

Increased Serum Soluble (Pro)renin Receptor Levels in Patients with Sarcopenia

International Journal of Endocrinology
Purpose. Sarcopenia is an advancing and widespread skeletal muscle condition characterized by the depletion of skeletal muscle mass. The (pro)renin receptor ((P)RR) is a multifaceted protein with both pathophysiological and physiological functions. (P)RR is cleaved to generate soluble (P)RR, whose blood concentration may reflect the expression level of
Satoshi Morimoto, Haruki Sasaki, Chikahito Suda, Atsuhiro Ichihara, Nobuyuki Ura   +4 more
openaire   +2 more sources

Loss of Soluble (Pro)renin Receptor Attenuates Angiotensin-II Induced Hypertension and Renal Injury. [PDF]

Circ Res, 2021
Ramkumar N, Stuart D, Peterson CS, Hu C, Wheatley W, Min Cho J, Symons JD, Kohan DE.   +7 more
europepmc   +1 more source

Site-1 Protease-Derived Soluble (Pro)Renin Receptor Contributes to Angiotensin II-Induced Hypertension in Mice. [PDF]

Hypertension, 2021
Feng Y, Peng K, Luo R, Wang F, Yang T.
europepmc   +1 more source

The (pro)renin receptor ((P)RR) can act as a repressor of Wnt signalling

, 2012
The (pro)renin receptor ((P)RR) and Wnt signalling are both involved in different diseases ranging from cardiac and renal end-organ damage to cancer.
Zaade, Daniela, Stawowy, Philipp, Zollmann, Frank S., Schmitz, Jennifer, Klare, Sabrina, Meyborg, Heike, Funke-Kaiser, Heiko, Schrezenmeier, Eva, Kirsch, Sebastian, Seidel, Kerstin, Bernhard, Sarah M., Goldin-Lang, Petra, Unger, Thomas   +12 more
core   +1 more source

Soluble (pro)renin receptor induces endothelial dysfunction and hypertension in mice with diet-induced obesity via activation of angiotensin II type 1 receptor. [PDF]

Clin Sci (Lond), 2021
Fu Z, Wang F, Liu X, Hu J, Su J, Lu X, Lu A, Cho JM, Symons JD, Zou CJ, Yang T.   +10 more
europepmc   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source