Results 161 to 170 of about 41,164 (267)

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

Advanced Science, Volume 13, Issue 26, 8 May 2026.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy, Zoe L. Chau, Sheng‐You Chen, Nanami Fujisawa, John J. Hill, Barnett M. Hsu, Joanne K. Liu, Karol W. Mai, James J. Lai   +8 more
wiley   +1 more source

Nanotechnology Meets Immunotherapy: Crosstalks Against Cancer

Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.
ABSTRACT Background The convergence of nanotechnology and immunotherapy has ushered in a transformative era in cancer treatment, offering new strategies to overcome pharmacokinetic limitations and immune evasion associated with conventional therapies. While immunotherapy, spanning checkpoint inhibitors, adoptive cell transfer, and cancer vaccines, has ...
Nima Javanmehr, Asal Moazzami Ashtyani, Robabehbeygom Ghafelehbashi, Fateme Mousavi, Hossein Teimouri   +4 more
wiley   +1 more source

Biomarkers of iron deficiency and prognosis in patients hospitalised with new-onset heart failure and a reduced left ventricular ejection fraction. [PDF]

Open Heart
Johansson JSM, Henrysson J, Basic C, Cleland JGF, Fu M, Ljungman C.   +5 more
europepmc   +1 more source

The Small Molecule H89 Facilitates Mesenchymal Stem Cell‐derived Extracellular Vesicle Release and Optimizes Therapeutic Efficacy in Liver Regeneration

Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
ABSTRACT The role of human umbilical cord mesenchymal stem cell‐derived extracellular vesicles (hUCMSC‐EVs) in liver regeneration is promising, yet their clinical translation is hampered by insufficient production. Current strategies targeting their secretion are inefficient and lack a clear mechanistic understanding.
Yu Fu, Yi Ma, Jiajun Zhang, Liwei Liang, Ting Li, Zeyi Guo, Zhongzhe Li, Lei Feng, Yi Wang, Guolin He, Shao Li, Yang Li, Xiaoping Xu, Hui Liao, Yi Gao   +14 more
wiley   +1 more source

Biomarker-Defined Iron Deficiency in Heavy Smokers with and without COPD and/or Emphysema. [PDF]

Int J Chron Obstruct Pulmon Dis
Hardang IM, Neumann K, Gjønnes GT, Strand TE, Ashraf H, Einvik G.   +5 more
europepmc   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Iron, the Essential Micronutrient: A Comprehensive Review of Regulatory Pathways of Iron Metabolism. [PDF]

Nutrients
Horváth A, Tamási K, Pap R, Jánosa G, Pandur E.   +4 more
europepmc   +1 more source

Reduction in Synaptic Vesicle Protein Abundance but Increased Amounts of Nsg2 and Lpcat1 in Cerebral Cortices Without the Endosomal SNARE Proteins Vti1a and Vti1b

PROTEOMICS, Volume 26, Issue 5, Page 86-97, May 2026.
ABSTRACT Absence of the endosomal SNAREs vti1a and vti1b results in perinatal death and severe neuronal phenotypes in mice, while lack of one of these proteins results in minor phenotypes. Proteomic differences were investigated to obtain a deeper insight into processes in which vti1a and vti1b are involved.
Julia Gottschalk, Katharina Kotschnew, Julia Hahn, Thomas Patschkowski, Gabriele von Fischer von Mollard   +4 more
wiley   +1 more source

Serum soluble transferrin receptor (sTfR) in HFpEF: associations with cardiac function and exercise tolerance. [PDF]

Eur J Med Res
Ma J, Zhao J, Jia G.
europepmc   +1 more source

Adverse Prognostic Impact of Pretransplant Serum Ferritin and Hepcidin on Survival Outcomes After Allogeneic Hematopoietic Stem Cell Transplantation

American Journal of Hematology, Volume 101, Issue 6, Page 1239-1243, June 2026.
Michelle Pirotte, Marianne Fillet, Laurence Seidel, Evelyne Willems, Sophie Servais, Fréderic Baron, Yves Beguin   +6 more
wiley   +1 more source