Results 151 to 160 of about 30,348 (310)

Mechanical Forces Guide Axon Growth through the Nigrostriatal Pathway in an Organotypic Model

Advanced Science, EarlyView.
Nano‐pulling is a magnetic nanoparticle‐based technology for guiding and promoting the axon growth of induced pluripotent stem cell‐derived dopaminergic neurospheres in vitro or neural progenitors transplanted in the brain tissue. Fine control of axon guidance is essential for reconstructing neural networks and restoring functional connectivity in the ...
Sara De Vincentiis, Elena Capitanini, Karen Kira, Claudia Dell'Amico, Jun Takahashi, Marco Onorati, Fabian Raudzus, Vittoria Raffa   +7 more
wiley   +1 more source

3D Brain Vascular Niche Model Captures Glioblastoma Infiltration, Dormancy, and Gene Signatures

Advanced Science, EarlyView.
This study developed a 3D brain vascular niche model that capture the key features of glioblastoma including perivascular infiltration, gene signature, dormancy and chemo resistance, by comparing 3D model with in vivo condition using identical glioma stem cells.
Vivian K. Lee, Rut Tejero, Nathaniel Silvia, Anirudh Sattiraju, Aarthi Ramakrishnan, Li Shen, Alexandre Wojcinski, Santosh Kesari, Roland H. Friedel, Hongyan Zou, Guohao Dai   +10 more
wiley   +1 more source

Placental RTN3L‐dependent ER‐Phagy Contributes to Fetal Testicular Dysplasia Upon Environmental Stress

Advanced Science, EarlyView.
Gestational environmental stress activates ER‐phagy by increasing placental Rtn3l mRNA N6‐methyladenosine modification, further inhibiting placental estradiol synthesis and contributing to fetal testicular dysplasia. This study demonstrates the early prevention and treatment of adult male infertility from the perspective of fetal‐derived diseases ...
Ye‐Xin Luo, Hua‐Long Zhu, Bin‐Bin Huang, Cheng‐Fang Sun, Xin‐Xin Zhang, Xin‐Run Wang, Yi‐Fan Hu, Xu‐Dong Zhang, Shen‐Dong Xu, Huan Zhou, Rui Pan, Wei Chang, Zhi Yuan, Yong‐Wei Xiong, Xiao‐Feng Xu, Ling‐Li Zhao, De‐Xiang Xu, Hua Wang   +17 more
wiley   +1 more source

Contrast Agent Clearance Dynamics and Diffusion in the Mouse Brain After Ventricular Administration

Advanced Science, EarlyView.
Schematic representation of contrast agent clearance by convective bulk flow from the ventricular spaces to the subarachnoid space on the ventral aspect of the brain, or by diffusion into the parenchyma across the pia‐glia or through the semi‐permeable ependyma. Abstract Fluid and solute exchange between cerebrospinal fluid (CSF) spaces and the central
Yann Decker, Andreas Müller, Steven T. Proulx   +2 more
wiley   +1 more source

Electronic Structure of Kramers Nodal‐Line Semimetal YAuGe and Anomalous Hall Effect Induced by Magnetic Rare‐Earth Substitution

Advanced Science, EarlyView.
The rare‐earth intermetallics YAuGe is identified as a Kramers nodal‐line semimetal, a topological state inherent to non‐centrosymmetric achiral lattices. Magnetic rare‐earth substitution induces an anomalous Hall effect, highlighting the impact of time‐reversal symmetry breaking on topological electronic states and offering insights into designing the
Takashi Kurumaji, Jorge I. Facio, Natsuki Mitsuishi, Shusaku Imajo, Masaki Gen, Motoi Kimata, Linda Ye, David Graf, Masato Sakano, Miho Kitamura, Kohei Yamagami, Kyoko Ishizaka, Koichi Kindo, Taka‐hisa Arima   +13 more
wiley   +1 more source

RSPO2 Coordinates with GDF9:BMP15 Heterodimers to Promote Granulosa Cell and Oocyte Development in Mice

Advanced Science, EarlyView.
RSPO2 and GDF9:BMP15 heterodimers—core components of oocyte‐secreted factors (OSFs)—coordinate to shape the molecular architecture of preantral granulosa cells via gene‐specific synergistic and antagonistic regulation, mediated through CTNNB1–SMAD2 signaling crosstalk.
Yingmei Wang, Hongjiang Li, Liji You, Shuhui Wang, Jinglei Bie, Ziyang Su, Lanying Shi, You‐Qiang Su   +7 more
wiley   +1 more source

Suppressing Mo‐Species Leaching in MoOx/A‐Ni3S2 Cathode for Stable Anion Exchange Membrane Water Electrolysis at Industrial‐Scale Current Density

Advanced Science, EarlyView.
This work develops a novel and highly efficient MoS2/Ni3S2 catalyst toward hydrogen evolution reaction (HER) for the anion exchange membrane water electrolyzer. During HER, the MoS2 on the electrode surface undergoes an oxidative dissolution and is redeposited as amorphous MoOx.
Husileng Lee, Guoheng Ding, Linqin Wang, Yunxuan Ding, Tang Tang, Licheng Sun   +5 more
wiley   +1 more source

Separating the Role of Mixing‐Entropy on the Dynamics of Glass‐Forming Liquids

Advanced Science, EarlyView.
This research innovates by distinguishing entropy’s impact from enthalpy in materials through micro‐alloying. It finds liquid fragility decreases with minimal alloying content or increased element diversity. This clarifies entropy’s role and supports the entropy‐driven glass transition, guiding new material design.
Qing‐Zhou Bu, Jia‐Xin Zhang, Hui‐Ru Zhang, Ran Li, Tao Zhang, Lin Liu, Peng Yu, Hai‐Bin Yu   +7 more
wiley   +1 more source

Use of Hupresin To Capture Red Blood Cell Acetylcholinesterase for Detection of Soman Exposure

, 2017
Seda Önder, Lawrence M. Schopfer, John R. Cashman, Özden Tacal, Rudolph C. Johnson, Thomas A. Blake, Oksana Lockridge   +6 more
openalex   +1 more source

A Smart Single‐Loop‐Mediated Isothermal Amplification Facilitates Flexible SNP Probe Design for On‐Site Rapid Differentiation of SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
The ssLAMP method amplifies the nucleic acid of pathogen and identifies SNP mutations. By combining the portable detection device with smartphone‐based analysis software, enables rapid, on‐site SNP detection and genotyping of SARS‐Cov‐2 Omicron variants, providing a cost‐effective and field‐deployable solution for precise pathogen identification in ...
Qijie Lin, Hongchao Gou, Xiaoyun Qu, Kaiyuan Jia, Yuhui Deng, Dan Li, Qianyi Cai, Yucen Liang, Xiaozhen Xu, Yanbin Li, Jianhan Lin, Letian Li, Yuhang Jiang, Shouwen Du, Lingcong Deng, Bailing Yan, Ruidong Liu, Chang Li, Jianmin Zhang, Ming Liao   +19 more
wiley   +1 more source