Results 211 to 220 of about 9,449 (276)

Dual-adjuvant mucosal vaccine leveraging mast cell and TLR9 agonists for protection against poxvirus infection.

open access: yesRSC Pharm
Murphy CT   +14 more
europepmc   +1 more source

Do publicly supported generic pharmacies improve financial risk protection? Findings from a nationally representative cross-sectional survey in India. [PDF]

open access: yesBMJ Open
Purohit N   +12 more
europepmc   +1 more source
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Monoclonal antibodies against soman: characterization of soman stereoisomers

Immunology Letters, 1992
Hybridomas were produced which expressed monoclonal anti-soman antibodies as determined by microtiter enzyme-linked-antibody immunoassay (EIA). Each of these antibodies was titrated using a competitive inhibition enzyme immunoassay (CIEIA) with a variety of test ligands. The ligands used included soman (a racemic mixture), sarin, tabun, and each of the
David E Lenz, Jeffrey J Yourick
exaly   +3 more sources

Survivors of soman poisoning: recovery of the soman LD50 to control value in the presence of extensive acetylcholinesterase inhibition

Archives of Toxicology, 1989
Initially, mice were pretreated with atropine (17.4 mg/kg; IP) and the oxime reactivator HI-6 (50 mg/kg; IP) 5 min prior to an injection of soman (287 micrograms/kg, SC); approximately 2.1 x LD50 dose). More than 95% of the mice survived this dose of soman with atropine and HI-6 pretreatment.
John G Clement
exaly   +3 more sources

Treatment of Poisoning by Soman

Toxicological Sciences, 1985
The efficacies of a number of drug treatment combinations in protecting guinea pigs against the lethal and incapacitating effects of soman (and sarin) have been determined. Incapacitation was studied using a swimming test which is a measure of gross motor performance.
L, Leadbeater, R H, Inns, J M, Rylands
openaire   +2 more sources

Characterization of soman-binding antibodies raised against soman analogs

Molecular Immunology, 1992
The production of antibodies against the highly toxic organophosphorus compound soman (GD) has been undertaken. Monoclonal antibodies were raised against two structural analogs of soman which served as haptens for immunization. In these soman analogs the chemically active P-F bond of the soman molecule was substituted by a P-OH group (which is ionized ...
M, Glikson   +5 more
openaire   +2 more sources

A method for generating toxic vapors of soman: Toxicity of soman by inhalation in rats

Toxicology and Applied Pharmacology, 1985
A method for administration of highly toxic chemicals by inhalation was developed. The model has three features of special interest: (1) a diffusion cell for producing a constant gas concentration, if necessary for several hours and days, (2) a small rapidly equilibrated inhalation chamber (1100 ml), and (3) complete isolation of the toxic chemicals ...
P, Aas   +3 more
openaire   +2 more sources

A pharmacodynamic model for soman in the rat

Toxicology Letters, 1988
A pharmacodynamic model for inhibition of acetylcholinesterase (AChE) by soman was developed to describe the intertissue differences in AChE inhibition, the dose response of AChE to inhibition by soman, and the effect of differences in xenobiotic metabolism on soman toxicity.
D M, Maxwell, C P, Vlahacos, D E, Lenz
openaire   +2 more sources

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