Results 221 to 230 of about 5,197 (259)
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Inactivation of sarin and soman by cyclodextrins in vitro
Experientia, 1987Cyclodextrins catalyzed the inactivation of sarin and soman but did not inactivate tabun and VX. Furthermore, sarin and soman showed greater affinity for beta-cyclodextrin than for alpha- or gamma-cyclodextrins. Thus beta-cyclodextrin appears to be an attractive starting material for the preparation of a catalyst able to inactivate sarin and soman more
B, Désiré, S, Saint-André
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Toxicology and Applied Pharmacology, 2004
The combined effects of physostigmine and procyclidine (antagonizing muscarinic, nicotinic, and NMDA receptors) were tested against various doses of soman. Physostigmine (0.1 mg/kg) in combination with procyclidine doses of 1, 3, or 6 mg/kg effectively prevented the development of convulsions and hippocampally monitored seizures when the doses of soman
Trond, Myhrer +3 more
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The combined effects of physostigmine and procyclidine (antagonizing muscarinic, nicotinic, and NMDA receptors) were tested against various doses of soman. Physostigmine (0.1 mg/kg) in combination with procyclidine doses of 1, 3, or 6 mg/kg effectively prevented the development of convulsions and hippocampally monitored seizures when the doses of soman
Trond, Myhrer +3 more
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Acute Inhalation Toxicity of Soman and Sarin in Baboons
Toxicological Sciences, 1990Adult baboons (Papio sp.; 8-12 kg) were anesthesized with sodium pentobarbital (20 mg/kg iv). The animals were instrumented for measurement of mean blood pressure (MBP), pulmonary artery pressure (PAP), ECG, arterial and mixed venous blood gases, lung volumes, lung pressures, and efferent phrenic nerve activity.
A, Anzueto +6 more
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Acta pharmacologica Sinica, 2003
To investigate the effect of nimodipine on the elimination of soman in rabbit blood and distribution of [3H]soman in mice.Chirasil capillary gas chromatographic analysis method with large volume injections was used to determine the concentration of C(+/-)P(-)soman in rabbit blood.
Jin-Tong, Li +5 more
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To investigate the effect of nimodipine on the elimination of soman in rabbit blood and distribution of [3H]soman in mice.Chirasil capillary gas chromatographic analysis method with large volume injections was used to determine the concentration of C(+/-)P(-)soman in rabbit blood.
Jin-Tong, Li +5 more
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Visual detection of soman metabolites in zebrafish
Analytical MethodsSoman, an organophosphate compound, is readily converted into pinacolyl methylphosphonic acid in the environment.
Xing-Xing Zong +5 more
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Problems in the therapy of soman poisoning
Fundamental and Applied Toxicology, 1981O L, Wolthuis, F, Berends, E, Meeter
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Enzymatic synthesis of sarin and soman
Biochemical Pharmacology, 1985M C, Sun, H, Zhang, T C, Chou
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