Results 11 to 20 of about 63,552 (337)

Mouse somatic cell nuclear transfer: What has changed and remained unchanged in 25 years [PDF]

open access: yesThe Journal of Reproduction and Development, 2023
Somatic cell nuclear transfer (SCNT) is the only reproductive technology used to produce individuals from somatic cells by transferring them to enucleated oocytes.
Kimiko INOUE
doaj   +2 more sources

Asymmetric nuclear reprogramming in somatic cell nuclear transfer? [PDF]

open access: greenBioEssays, 2007
AbstractDespite the progress achieved over the last decade after the birth of the first cloned mammal, the efficiency of reproductive cloning remains invariably low. However, research aiming at the use of nuclear transfer for the production of patient‐tailored stem cells for cell/tissue therapy is progressing rapidly. Yet, reproductive cloning has many
Pasqualino Loi   +4 more
openalex   +7 more sources

Somatic Cell Nuclear Transfer [PDF]

open access: bronze, 2007
Nuclear remodeling and nuclear reprogramming for making transgenic pigs by nuclear transfer.- Somatic cell nuclei in cloning: strangers traveling in a foreign land.- Cloning cattle: the methods in the madness.- Centrosome inheritance after fertilization and nuclear transfer in mammals.- Developmental, behavioral, and physiological phenotype of cloned ...
Peter Šutovský
openalex   +3 more sources

Applications of somatic cell nuclear transfer in goats

open access: yesJournal of Advanced Veterinary and Animal Research, 2014
A number of animals with genetically identical appearance can be produced by somatic cell nuclear transfer (SCNT). From current advancement of SCNT and molecular techniques, production of a transgenic animal becomes easier. Although cloning efficiency in
Ton Yoisungnern, Ashit Kumar Paul
doaj   +3 more sources

Reproductive ability of minipigs as surrogates for somatic cell nuclear transfer [PDF]

open access: yesJournal of Animal Science and Technology
Pigs are genetically, anatomically, and physiologically similar to humans. Recently, pigs are in the spotlight as a suitable source animal for xenotransplantation.
Joonho Moon   +5 more
doaj   +2 more sources

Lysophosphatidic acid improves development of porcine somatic cell nuclear transfer embryos [PDF]

open access: yesJournal of Animal Science and Technology
This study was conducted to investigate whether lysophosphatidic acid (LPA) could improve the development of porcine somatic cell nuclear transfer (SCNT) embryos.
Ling Sun   +5 more
doaj   +2 more sources

Cloned ferrets produced by somatic cell nuclear transfer

open access: greenDevelopmental Biology, 2006
Somatic cell nuclear transfer (SCNT) offers great potential for developing better animal models of human disease. The domestic ferret (Mustela putorius furo) is an ideal animal model for influenza infections and potentially other human respiratory diseases such as cystic fibrosis, where mouse models have failed to reproduce the human disease phenotype.
Ziyi Li   +8 more
openalex   +6 more sources

XIST Derepression in Active X Chromosome Hinders Pig Somatic Cell Nuclear Transfer

open access: yesStem Cell Reports, 2018
Summary: Pig cloning by somatic cell nuclear transfer (SCNT) remains extremely inefficient, and many cloned embryos undergo abnormal development. Here, by profiling transcriptome expression, we observed dysregulated chromosome-wide gene expression in ...
Degong Ruan   +26 more
doaj   +2 more sources

Somatic cell nuclear transfer [PDF]

open access: yesNature, 2002
Cloning by nuclear transfer from adult somatic cells is a remarkable demonstration of developmental plasticity. When a nucleus is placed in oocyte cytoplasm, the changes in chromatin structure that govern differentiation can be reversed, and the nucleus can be made to control development to term.
Tim King   +9 more
openaire   +7 more sources

Interspecific Nuclear Transfer Blastocysts Reconstructed from Arabian Oryx Somatic Cells and Domestic Cow Ooplasm

open access: yesVeterinary Sciences, 2022
Cloning, commonly referred to as somatic cell nuclear transfer (SCNT), is the technique of enucleating an oocyte and injecting a somatic cell into it. This study was carried out with interspecific SCNT technology to clone the Arabian Oryx utilizing the ...
Aiman A. Ammari   +4 more
doaj   +1 more source

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