Expanding the Clinical Spectrum of VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome: The First Report of Histologically Confirmed Neutrophilic Colitis With Rare Muscular and Pancreatic Involvement. [PDF]
El Tahech S +3 more
europepmc +1 more source
NK cells present in EOC‐associated ascites retain elements of the conventional NK cell program while displaying a transcriptional profile distinct from peripheral blood NK cells. This profile encompasses biological programs usually associated with the CD56bright NK cell functions, which is consistent with transcriptional remodeling rather than complete
Caroline Natânia de Souza‐Araújo +10 more
wiley +1 more source
Physiological, genetic and inflammatory factors influencing somatic cell count in goat milk: a review. [PDF]
Einorytė J +4 more
europepmc +1 more source
ABSTRACT The tumour microenvironment (TME) comprises a dynamic network of structural, cellular, and signalling components that interact to influence tumour development. Immune cells play a key role in recognizing and eliminating cancer cells through detection of tumour‐derived membrane and secreted proteins processed in the endoplasmic reticulum (ER ...
Yew Hwang Chee +4 more
wiley +1 more source
Increased reluctant vesicles underlie synaptic depression by GPR55 in axon terminals of rat cerebellar Purkinje cells. [PDF]
Inoshita T, Kawaguchi SY.
europepmc +1 more source
α‐Synuclein is a presynaptic protein extensively studied for its role in Parkinson's disease; however, its native function remains unclear. Here, we show that modest (approximately 2‐fold) overexpression of α‐synuclein in cultured neurons, at levels observed in familial synucleinopathies with SNCA triplication, impairs the endocytic retrieval of the ...
Elyas H. Arvell +7 more
wiley +1 more source
Secreted molecules as modulators of somatic embryogenesis efficiency - an overview. [PDF]
Pires R +4 more
europepmc +1 more source
The Skin‐Lightening Efficacy and Mechanisms of Botanical Extracts: A Comprehensive Review
ABSTRACT Background Skin pigmentation is regulated by a complex network involving melanogenesis, melanosome transfer, oxidative stress, environmental stimuli, and epidermal turnover. Botanical extracts and phytochemicals have attracted increasing interest as potential skin‐lightening agents. This review evaluates their efficacy, mechanisms, and safety.
Siting Yang +6 more
wiley +1 more source
The interplay between epidermal cells and the cutaneous sensory nervous: a systematic review. [PDF]
Wang F, An X, Fan D, Shang J.
europepmc +1 more source
Seminal Extracellular Vesicles as Molecular Modulators of Male Reproductive Function
ABSTRACT Extracellular vesicles (sEVs) contained in seminal plasma (SP) maintain, in concert with free SP‐components (proteins, hormones, cytokines, metabolites and antioxidants) under an endocrine umbrella the functional in vivo homeostasis of ejaculated spermatozoa. The sEVs define a generic mixture of nanovesicles delivered by male epithelial cells,
Heriberto Rodriguez‐Martinez +3 more
wiley +1 more source

