Results 71 to 80 of about 6,476 (161)
Maturation of spinal motor control through developmental changes in ion currents
Abstract figure legend Ion channels of spinal neurons have been shown to change during development in a wide range of species. These changes occur at specific stages of development. An important developmental process is the maturation of motor control by which the body acquires new movements or refines movements already present.
Stephanie F. Gaudreau, Tuan V. Bui
wiley +1 more source
Endotoxins and Biological Implications—Review
Graphical overview of endotoxin sources, exposure routes, biological effects, detection methods, and routes of elimination. ABSTRACT Endotoxins, also known as lipopolysaccharides (LPSs), are structural components of the outer membrane of Gram‐negative bacteria and some cyanobacteria.
Uzair Ishtiaq +5 more
wiley +1 more source
Abstract An ultrastructural morphometric analysis of the postnatal development of the lung in the gray short‐tailed opossum (Monodelphis domestica) has been conducted to evaluate the morphofunctional status of this poorly developed marsupial lung immediately following parturition.
Kirsten Ferner
wiley +1 more source
Human brain matters: Navigating the neuropathology of COVID‐19
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland +4 more
wiley +1 more source
Transverse Histological Analysis of Scalp Seborrheic Dermatitis: A Novel Perspective
ABSTRACT Background Seborrheic dermatitis is a chronic inflammatory disease affecting seborrheic areas of the skin, including the scalp. It is often confused with scalp psoriasis due to similar clinical and histopathological features. Objective This study described microscopic changes in the pilosebaceous unit in seborrheic dermatitis (SDS) using cross‐
Tatiane Elen de Souza +2 more
wiley +1 more source
This study systematically compares small extracellular vesicles (sEVs) derived from four neural cell lines, revealing how cellular origin shapes vesicle biophysical properties and proteomic cargo. Distinct, lineage‐specific signatures linked to neuronal, astrocytic, and microglial functions are identified, highlighting the importance of cell source ...
Muhammad Waqas Salim +4 more
wiley +1 more source
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva +8 more
wiley +1 more source
Proteomic Signatures of Noise‐Induced Hearing Loss in the Mouse Cochlea
ABSTRACT Hearing loss affects over 1.5 billion people worldwide and has substantial social, educational, and economic consequences. Although genetic studies have identified numerous hearing‐loss‐associated genes, the molecular changes accompanying noise‐induced hearing loss (NIHL) remain incompletely understood.
Ana Carla Batissoco +6 more
wiley +1 more source
ABSTRACT This case reports a primigravida with Type 1 von Willebrand disease experiencing hematuria and gingival bleeding despite prophylaxis. Although pregnancy raises factor levels, her response was insufficient. Desmopressin successfully controlled mucosal hemorrhage, avoiding antifibrinolytics due to obstructive risk.
Jose Luis Rojas‐Oviedo +5 more
wiley +1 more source
Current Management & Limitations: Traditional auditory devices lack genetic curative potential and yield variable, non‐physiological hearing outcomes. OTOF gene therapy has shown promising clinical outcomes with dual‐AAV therapy. GJB2 gene therapy remains an emerging approach with significant translational challenges. Advances in vector design and cell‐
Jiahui Zhao, Mengzhao Xun, Yu Sun
wiley +1 more source

