Results 241 to 250 of about 13,712 (280)
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Somatomedin activity in the Mauriac syndrome

The Journal of Pediatrics, 1980
7. Sirinavin S, and McCracken GH: Primary suppurative myositis in children, Am J Dis Child 133:263, 1979. 8. Blair DC, Carroll M, and Silva J: Localization of infectious process with gallium citrate Ga 67, JAMA 230:82, 1974. 9. Hopkins GB, Kan M, and Mende CW: Early 67 Ga scintigraphy for the localization of abdominal abscesses, J Nucl Med 16:990, 1975.
Orville C. Green   +3 more
openaire   +3 more sources

The effects of insulin and growth hormone on the release of somatomedin by the isolated rat liver.

Endocrinology, 1976
Livers from hypophysectomized (hypox) rats were perfused with oxygenated Waymouth's medium in a system which permitted continuous recirculation for separate 30 minute periods after which fresh medium was supplied.
William H. Daughaday   +2 more
semanticscholar   +1 more source

Immunoreactive Somatomedin A in Human Serum*

The Journal of Clinical Endocrinology & Metabolism, 1979
A RIA has been developed for somatomedin A (SM-A) utilizing Sepharose-bound antibodies. This assay, measuring SM-A, the insulin-like growth factors 1 and 2, and somatomedin C, allows determination in serum samples. In comparison with a serum standard, the mean serum levels in patients with acromegaly or GH deficiency and healthy subjects were 8.7 %/- 0.
Gösta Enberg   +3 more
openaire   +3 more sources

The biosynthesis of somatomedins and their role in the fetus

Acta Endocrinologica, 1986
Abstract The somatomedins are a family of hormones consisting of insulin-like growth factors 1 and 2 as well as their variant forms. These peptides have a direct growth-promoting action on fetal cells mediated through their interaction with Type I and II receptors distributed throughout the fetus.
Christine Carlsson-Skwirut   +1 more
openaire   +3 more sources

Plasma concentrations of somatomedin-C in hypophysectomized, dwarf and intact growing domestic fowl as determined by heterologous radioimmunoassay.

Journal of Endocrinology, 1985
The application of a human somatomedin-C radioimmunoassay for the determination of somatomedin-C in chicken plasma has been examined. Parallel inhibition of binding of 125I-labelled somatomedin-C to antisera raised against somatomedin-C was observed with
L. Huybrechts   +4 more
semanticscholar   +1 more source

Nutrition and somatomedin. XI. Studies of somatomedin inhibitors in rats with streptozotocin-induced diabetes

Diabetes, 1983
Diabetics may have normal somatomedins by radioimmunoassay yet decreased somatomedin activity by bioassay. The discrepancy appears due to circulating inhibitory factors; inhibitors in whole diabetic serum antagonize the action of both somatomedins and insulin via noncompetitive interactions.
C K Matheson   +3 more
openaire   +3 more sources

Local injections of human or rat growth hormone or of purified human somatomedin-C stimulate unilateral tibial epiphyseal growth in hypophysectomized rats.

Endocrinology, 1985
The growth-promoting actions of GH are thought to be mediated by somatomedin(s) (Sms), but unilateral bone growth in hypophysectomized (HX) rats given local injections of human (h) GH has been reported. Using slightly different methods, we have confirmed
S. Russell, E. Spencer
semanticscholar   +1 more source

A RAPID SIMPLIFIED BIOASSAY FOR SOMATOMEDIN

Journal of Endocrinology, 1978
A simplified, more rapid bioassay for the estimation of somatomedin activity, based on the porcine costal cartilage bioassay, is described. A micro-scale system based on the porcine costal cartilage assay is also described. These assay systems showed no decrease in sensitivity or precision, compared with other methods, as a result of the modifications.
A. M. Taylor, G. S. G. Spencer
openaire   +3 more sources

Somatomedin carrier proteins

Molecular and Cellular Endocrinology, 1984
The somatomedins, such as the insulin-like growth factors I and II, somatomedins A and C, and multiplication-stimulating activity, are small, growth hormone dependent polypeptides which are the assumed mediators of growth hormone action on extraskeletal tissues.
openaire   +3 more sources

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