Results 91 to 100 of about 57,549 (242)
Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia
Journal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer +4 more
wiley +1 more source
Journal of Anatomy, Volume 246, Issue 4, Page 479-504, April 2025.Chronic silencing of subsets of layer 5 projection neurons has distinct effects on the laminar distribution of PV interneurons and the perineuronal nets in the adult primary motor and somatosensory cortex. Abstract Neural networks are established throughout cortical development, which require the right ratios of glutamatergic and GABAergic neurons ...
Florina P. Szabó +4 more
wiley +1 more source
The MacBrain Resource Center (MBRC) rhesus macaque embryonic brain histology datasets
Journal of Anatomy, EarlyView.We introduce the MacBrain Resource Center (MBRC) Collections of rhesus macaque embryonic brain tissue. Here, we illustrate histo‐ and immunohistology from our dynamically growing Collection 6, which currently contains >10,000 zoomable and downloadable images from n = 14 male and female embryos from early to late in gestation.
Valeria Mendoza‐Silva +11 more
wiley +1 more source
Journal of Anatomy, EarlyView.The MacBrain Resource Center (MBRC) postnatal rhesus macaque brain histology datasets are organized into Collections that promote cost‐effective de novo research. This article provides examples from Collections 5, 6, and 7 and describes the histo‐ and immunohistochemical (IHC) processing of materials for Collection 6.
Valeria Mendoza‐Silva +19 more
wiley +1 more source
Transcriptomic profiling of subpopulations of mouse embryonic subplate neurons
Journal of Anatomy, EarlyView.To study gene expression in subpopulations of cortical subplate neurons (Lpar1‐EGFP‐positive and D1B‐positive SpN clusters), we applied gene expression profiling, including bulk microarray analysis, single‐cell RNA sequencing (scRNA‐seq), and Visium spatial transcriptomics, and identified both overlapping and unique gene expression signatures ...
Hitomi Achiwa +8 more
wiley +1 more source
Journal of Anatomy, EarlyView.GABAergic interneuron populations in the human prefrontal cortex (PFC) show distinct laminar distributions, with calretinin‐positive (CR+) neurons predominating in upper cortical layers. The orbitomedial PFC (BA14r) has a higher proportion of CR+ neurons than the dorsolateral PFC (BA9), with regional differences in interneuron composition being most ...
Ivan Banovac +4 more
wiley +1 more source
Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli +12 more
wiley +1 more source
Amacrine cell inputs to OFF midget ganglion cells in macaque retina
The Journal of Physiology, EarlyView.Abstract figure legend The goal of this study was to explain the findings from physiological studies that OFF midget ganglion cells had larger receptive field centers than expected from their dendritic field diameters. First, we confirmed that OFF mRGCs (OFF MGC) receive input from diffuse bipolar cells (DB) as well as OFF midget bipolar cells (FMB ...
David W. Marshak +8 more
wiley +1 more source
Endocrine and androgenic response to altitude training in professional cyclists
The Journal of Physiology, EarlyView.Abstract figure legend Steroidal and endocrine variables are altered during altitude training. Abstract This study investigated endocrine and steroidal blood markers in 31 male elite cyclists monitored over 7 weeks, including a 3 week altitude training camp either at 2050 m (n = 19) or 3000 m (n = 12).
Raphael Faiss +11 more
wiley +1 more source
DEN Open, Volume 7, Issue 1, April 2027.Type I gastric neuroendocrine tumors (T1‑GNETs) often present as multiple lesions, complicating treatment. This retrospective case series study evaluates antrectomy outcomes in eight patients with persistent multiple T1‑GNETs during 2005–2023. Following antrectomy, tumor regression was observed in two patients and complete disappearance in six, with ...
Yuki Morita +9 more
wiley +1 more source