Results 101 to 110 of about 76,206 (274)

Somatostatin and Alzheimer's disease

open access: yes, 1995
One of the most consistent neurochemical deficits in Alzheimer's disease is a reduction in cortical somatostatin concentrations. The probability of a predominant regulatory change is heightened by the finding that 90% of somatostatin positive ...
Vécsei László, Klivényi Péter
core   +1 more source

Intraoperative carcinoid syndrome during small-bowel neuroendocrine tumour surgery

open access: yesEndocrine Connections, 2018
Only few descriptions of intraoperative carcinoid syndrome (ioCS) have been reported. The primary objective of this study was to describe ioCS. A second aim was to identify risk factors of ioCS.
Myrtille Fouché   +11 more
doaj   +1 more source

Somatostatin and cancer

open access: yesMetabolism, 1996
The potential role of somatostatin (SRIF) in the diagnosis and treatment of nonendocrine human cancers is reviewed. There have been many reports of the growth-inhibitory activity of SRIF on normal and transformed cells in vitro. Many processes involved in malignant tumor growth depend on autocrine growth mechanisms, and somatostatin receptors (ssts ...
openaire   +2 more sources

Totalsynthese von Somatostatin-28 (Big-Somatostatin) / Total Synthesis of Somatostatin-28 (Big Somatostatin)

open access: yesZeitschrift für Naturforschung B, 1980
The total synthesis of the octacosapeptide corresponding to the proposed primary structure of porcine somatostatin-28, a possible precursor of somatostatin, is described. The primary structure of somatostatin-28 corresponds to that of somatostatin elongated at the N-terminus by a tetradecapeptide sequence.
E. Wünsch   +6 more
openaire   +1 more source

Review of nutrition management of pediatric intestinal pseudo‐obstruction

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Chronic intestinal pseudo‐obstruction (CIPO) is a rare, heterogeneous, and debilitating disorder characterized by profound intestinal dysmotility and severe nutrition challenges. Its presentation resembles that of mechanical bowel obstruction, but CIPO occurs in the absence of luminal obstruction.
Senthilkumar Sankararaman   +5 more
wiley   +1 more source

Somatostatin receptor: Scintigraphy and radionuclide therapy

open access: yes, 1996
Peptide receptor scintigraphy is more sensitive at the biological than anatomical level, in contrast to conventional imaging, which it complements. Neuroendocrine tumours have the most somatostatin receptors in vitro and their metastases are somatostatin
Kooij, PPM   +8 more
core   +1 more source

Local axonal morphology guides the topography of interneuron myelination in mouse and human neocortex

open access: yeseLife, 2019
GABAergic fast-spiking parvalbumin-positive (PV) interneurons are frequently myelinated in the cerebral cortex. However, the factors governing the topography of cortical interneuron myelination remain incompletely understood.
Jeffrey Stedehouder   +10 more
doaj   +1 more source

Endoscopic Treatment for Esophagogastric Variceal Bleeding in Patients With Acute‐on‐Chronic Liver Failure: An Observational Study

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
In patients with acute‐on‐chronic liver failure (ACLF), esophagogastric variceal bleeding (EGVB) represents a critical complication associated with high short‐term mortality. This study evaluated the efficacy of endoscopic treatment in this specific population and identified prognostic factors associated with 6‐week rebleeding and mortality.
Yanan Sun   +7 more
wiley   +1 more source

Nonpeptide somatostatin receptor agonists specifically target ocular neovascularization via the somatostatin type 2 receptor

open access: yes, 2008
PURPOSE: To define the molecular pharmacology underlying the antiangiogenic effects of nonpeptide imidazolidine-2,4-dione somatostatin receptor agonists (NISAs) and evaluate the efficacy of NISA in ocular versus systemic delivery routes in ocular disease
Shaw, Lynn C   +13 more
core   +1 more source

Genetische Analyse des Somatostatin-Systems [PDF]

open access: yes, 2005
Somatostatin ist ein Molekül mit multifunktinonellem Charakter, dem Neurotransmitter-, Neuromodulator- und (Neuro)-Hormoneigenschaften zugeschrieben werden.
Zeyda, Thomas
core   +1 more source

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