ABSTRACT Seasonal photoperiodic cycles regulate energy rheostasis in many animals. Brown adipose tissue (BAT) and the liver are key metabolic organs that show remarkable plasticity in response to photoperiodic conditions. Prolactin (PRL) and thyroid hormones are endocrine signals that transmit neural‐derived photoperiodic time measurement encoding to ...
Sayantan Sur +5 more
wiley +1 more source
Effects of SRIH-14 on ACTH cells in male rats [PDF]
Trifunović Svetlana +4 more
doaj +1 more source
Delta-Cell Area is Unchanged in Human Pregnancy: Evidence From Immunohistochemistry. [PDF]
Seedat F +7 more
europepmc +1 more source
Gastric duplication cyst causing hypergastrinemia in an infant
Abstract Gastric duplication cysts are rare congenital anomalies, with fewer than 10% occurring in the stomach. We report a 14‐month‐old girl presenting with failure to thrive, recurrent emesis, hematemesis, and severe duodenitis with ulceration. Laboratory evaluation revealed marked hypergastrinemia (1781 pg/mL), and initial imaging was unrevealing ...
Nathan Bryan, Ian Leibowitz
wiley +1 more source
Type 2 Diabetes Mellitus: Molecular Pathogenesis and Therapeutic Interventions
This graphical summary illustrates the multiorgan therapeutic landscape for Type 2 diabetes mellitus (T2D), integrating molecular pathogenesis with modern treatment strategies. It depicts how current interventions, including SGLT2 inhibitors, GLP‐1 receptor agonists, and insulin secretagogues, target key organs—kidney, pancreas, gastrointestinal tract,
Shinuan Fei +9 more
wiley +1 more source
New Pathological Insights into Biomarkers for Multimodal Therapeutic Approach in Hepatic Neuroendocrine Tumors: A Detailed Case Report. [PDF]
Tsai YC, Lin CH, Hung CH, Ou JJ, Lee YT.
europepmc +1 more source
Antibody–Drug Conjugates and Peptide–Drug Conjugates: Current Understandings and Future Perspectives
The graphic summarizes the design principles, intracellular trafficking, clinical progress, challenges, and future directions of antibody–drug conjugates (ADCs) and peptide–drug conjugates (PDCs). ADCs consist of a tumor‐targeting antibody, a chemical linker, and a potent payload, whereas PDCs use peptide ligands to deliver cytotoxic, radionuclide, or ...
Ruxi Zheng +9 more
wiley +1 more source
Review of nutrition management of pediatric intestinal pseudo‐obstruction
Abstract Chronic intestinal pseudo‐obstruction (CIPO) is a rare, heterogeneous, and debilitating disorder characterized by profound intestinal dysmotility and severe nutrition challenges. Its presentation resembles that of mechanical bowel obstruction, but CIPO occurs in the absence of luminal obstruction.
Senthilkumar Sankararaman +5 more
wiley +1 more source
A Case of Primary Pulmonary Meningioma With Slow Enlargement Over a 9‐Year Period
Primary pulmonary meningioma (PPM) is an extremely rare benign tumour that often remains asymptomatic. Although most cases are incidentally detected as solitary pulmonary nodules on chest imaging, reports on their long‐term clinical courses remain limited. Herein, we report a case of PPM with slow growth over a nine‐year period.
Kazuki Sugata +3 more
wiley +1 more source
Radiopharmaceutical Theranostics in Primary Adrenal Malignancies: A Surgeon's Perspective. [PDF]
Laskou S +9 more
europepmc +1 more source

