Results 141 to 150 of about 84,280 (274)

Transcriptomic profiling of subpopulations of mouse embryonic subplate neurons

Journal of Anatomy, EarlyView.
To study gene expression in subpopulations of cortical subplate neurons (Lpar1‐EGFP‐positive and D1B‐positive SpN clusters), we applied gene expression profiling, including bulk microarray analysis, single‐cell RNA sequencing (scRNA‐seq), and Visium spatial transcriptomics, and identified both overlapping and unique gene expression signatures ...
Hitomi Achiwa, Yuichiro Hara, Hideya Kawaji, Minori Oshima, Noe Kaneko, Ayumu Morioka, Anna Hoerder‐Suabedissen, Zoltán Molnár, Chiaki Ohtaka‐Maruyama   +8 more
wiley   +1 more source

Regional specialization of upper‐layer inhibitory interneuron organization in the human prefrontal cortex

Journal of Anatomy, EarlyView.
GABAergic interneuron populations in the human prefrontal cortex (PFC) show distinct laminar distributions, with calretinin‐positive (CR+) neurons predominating in upper cortical layers. The orbitomedial PFC (BA14r) has a higher proportion of CR+ neurons than the dorsolateral PFC (BA9), with regional differences in interneuron composition being most ...
Ivan Banovac, Marija Baković, Davor Mayer, Dora Sedmak, Zdravko Petanjek   +4 more
wiley   +1 more source

Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli, Sara Alvente, Stefano Bastianini, Chiara Berteotti, Elisabetta Ciani, Elenia Cinelli, Viviana Lo Martire, Giorgio Medici, Tommaso Mello, Elena Miglioranza, Alessandro Silvani, Donatella Mutolo, Giovanna Zoccoli   +12 more
wiley   +1 more source

Amacrine cell inputs to OFF midget ganglion cells in macaque retina

The Journal of Physiology, EarlyView.
Abstract figure legend The goal of this study was to explain the findings from physiological studies that OFF midget ganglion cells had larger receptive field centers than expected from their dendritic field diameters. First, we confirmed that OFF mRGCs (OFF MGC) receive input from diffuse bipolar cells (DB) as well as OFF midget bipolar cells (FMB ...
David W. Marshak, Andrea S. Bordt, Emma R. Yang, Joel N. Yearick, Marcus Mazzaferri, James A. Kuchenbecker, Judith Mosinger Ogilvie, Sara S. Patterson, Jay Neitz   +8 more
wiley   +1 more source

Endocrine and androgenic response to altitude training in professional cyclists

The Journal of Physiology, EarlyView.
Abstract figure legend Steroidal and endocrine variables are altered during altitude training. Abstract This study investigated endocrine and steroidal blood markers in 31 male elite cyclists monitored over 7 weeks, including a 3 week altitude training camp either at 2050 m (n = 19) or 3000 m (n = 12).
Raphael Faiss, Bastien Krumm, Claes Cubel, Magnus Bak Klaris, Lasse Vestli Baekken, Yvette Dehnes, Jenna Goodrum, Geoff Miller, James Spragg, Martin Faulhaber, Francesco Botrè, Carsten Lundby   +11 more
wiley   +1 more source

¿Son útiles la somatostatina y sus análogos (octreótido y lanreótido) en el manejo del paciente con fístula entero-cutánea?: Revisión sistemática de la literatura

Revista Colombiana de Cirugía
Introducción. Las fístulas entero-cutáneas son una complicación infrecuente pero catastrófica para el paciente quirúrgico. En su manejo, el uso de la somatostatina y de sus análogos (octreótido/ lanreótido) se indica con frecuencia pero los resultados ...
Luis Carlos Domínguez, Álvaro Enrique Sanabria, Neil Valentín Vega, Camilo Osorio   +3 more
doaj  

The contribution of peripheral nerves to the pleasure from scratching an itch: Evidence from a neuronopathy participant

The Journal of Physiology, EarlyView.
Abstract figure legend Acute itch was experimentally induced using histamine and cowage in control participants (with no neuronopathy) and in IW, a participant with a large‐fibre sensory neuronopathy resulting in the loss of Aβ afferent function below C3, at the same time as largely preserving Aδ and C‐fibre function.
Adarsh D. Makdani, Andrew G. Marshall, Jonathan Cole, Francis McGlone   +3 more
wiley   +1 more source

The last‐step integrator thesis: Heterarchical control of the mammalian gastrointestinal tract

The Journal of Physiology, EarlyView.
Abstract figure legend Heterarchy of control of the gastrointestinal tract. The production mechanisms (i.e. epithelial cells and muscles) are shown at the bottom in green. Above them are some of the many mechanisms that provide control inputs to these production mechanisms.
William Bechtel, Leonardo Bich
wiley   +1 more source

Metabolic changes in response to food intake in somatostatin 1.1 deficient zebrafish

Somatostatin is a multifunctional hormone with several genes in teleost fishes. A zebrafish CRISPR/Cas9 knockout of the somatostatin 1.1 ( sst1.1 ) with persistent hyperglycaemia and hyperlipidaemia displayed reduced fecundity when fed brine shrimp ad ...
Canario, Adelino, Gao, Jing, Yuan, Huiming, Chen, Jie, Liu, Lu   +4 more
core   +1 more source

Clinical Outcomes of Antrectomy for Patients With Multiple Type I Gastric Neuroendocrine Tumors: A Case Series

DEN Open, Volume 7, Issue 1, April 2027.
Type I gastric neuroendocrine tumors (T1‑GNETs) often present as multiple lesions, complicating treatment. This retrospective case series study evaluates antrectomy outcomes in eight patients with persistent multiple T1‑GNETs during 2005–2023. Following antrectomy, tumor regression was observed in two patients and complete disappearance in six, with ...
Yuki Morita, Ken Namikawa, Kaoru Nakano, Wataru Kurihara, Hiroyuki Yamamoto, Yusuke Horiuchi, Akiyoshi Ishiyama, Toshiyuki Yoshio, Souya Nunobe, Toshiaki Hirasawa   +9 more
wiley   +1 more source