Results 131 to 140 of about 57,549 (242)

Conservative management of a delayed enterocutaneous fistula following emergency distal gastrectomy using sequential somatostatin analogues. [PDF]

J Surg Case Rep
Zalums A, Hibberd A.
europepmc   +1 more source

Redefining the Role of Chemotherapy and Targeted Cytotoxic Delivery in Lung Neuroendocrine Tumors

Thoracic Cancer, Volume 17, Issue 16, August 2026.
Perioperative chemotherapy utility remains uncertain and lacks universal standardization. Platinum/etoposide shows suboptimal efficacy in lung NET (neuroendocrine tumors); oral alkylators (temozolomide) alone or in combination (e.g., with capecitabine), and cabozantinib offer promising disease control.
Alice Laffi, Giuseppe Lamberti, Anna La Salvia   +2 more
wiley   +1 more source

Current treatment landscape of acromegaly.

J Clin Endocrinol Metab
Castinetti F, Ioachimescu AG.
europepmc   +1 more source

<i>C. elegans</i> somatostatin/allatostatin C signaling regulates sleep, metabolism, survival, and memory via a sleep-active neuron. [PDF]

Sci Adv
Park B, Mohsen L, Busack I, Uhlig L, Rossi L, Pollmeier G, Geens E, Istiban MN, Mandal S, Savio RD, Beets I, Stetak A, Bringmann H.   +12 more
europepmc   +1 more source

Prevention of microglial activation and postoperative cognitive deficits by positive allosteric modulation of α5‐GABAA receptors

British Journal of Pharmacology, Volume 183, Issue 16, Page 4836-4854, August 2026.
Background and Purpose Long‐lasting cognitive deficits after surgery in aged individuals, referred to as perioperative neurocognitive disorder (NCD), are a significant public health concern. Such postoperative cognitive deficits are dependent on the presence of microglia in the brain, which, when activated, trigger neuroinflammation.
Jinrui Lyu, Rajasekar Nagarajan, Dishary Sharmin, Prithu Mondal, Maltesh Kambali, Muxiao Wang, Jinyan Zhou, Makoto Inoue, James M. Cook, Uwe Rudolph   +9 more
wiley   +1 more source

Functional profiling of somatostatin receptors identifies somatostatin receptor subtype 2 as a vulnerability in Succinate Dehydrogenase SDHB-deficient pheochromocytomas and paragangliomas. [PDF]

Mol Biomed
García-Vioque V, Pedraza-Arevalo S, Moreno-Montilla MT, Rivero-Cortés E, Blázquez-Encinas R, Mangili F, Arroba E, Herrera-Martínez AD, Culler MD, Gálvez-Moreno MÁ, Barlier A, Botella LM, Robledo M, Castaño JP, Ibáñez-Costa A.   +14 more
europepmc   +1 more source

Inflammatory Cytokines Impair Glucagon Expression and Secretion in Pancreatic α‐Cells

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7149-7160, August 2026.
ABSTRACT Aims Insulin resistance and obesity‐associated inflammation are key drivers in the pathogenesis of Type 2 diabetes mellitus (T2DM). Whilst inflammatory cytokines are well known to impair β‐cell function, their impact on pancreatic α‐cells and glucagon (GCG) regulation remains poorly understood. In this study, we investigated the effects of the
Caroline Bickelmann, Cedric Wilden, Leticia Prates‐Roma, Matthias W. Laschke, Emmanuel Ampofo, Selina Wrublewsky   +5 more
wiley   +1 more source

Adenoma receptors and histologic characteristics determining management outcomes.

J Clin Endocrinol Metab
Wildemberg LE, Gadelha MR.
europepmc   +1 more source

Somatostatin and its analogs in the management of postoperative pancreatic fistulas: A comprehensive review. [PDF]

World J Gastrointest Surg
Lazaridou L, Dimaki A, Vakalou K, Zervas V, Papadopoulos P, Koumarelas KE, Christodoulidis G.   +6 more
europepmc   +1 more source

Decoding Brain Development and Function Through GABAergic Inhibitory Neurons

European Journal of Neuroscience, Volume 64, Issue 3, August 2026.
Interneuron subtype specification occurs case by case. Whereas some interneurons are specified very early, at the progenitor level, other interneurons develop final features during migration into the migratory stream or upon integration into specific cortical layers. The concept that interneuron specification can be significantly influenced by external
Renata Batista‐Brito, Christian Mayer, Mercedes Paredes, Carla G. Silva   +3 more
wiley   +1 more source