Results 81 to 90 of about 117,172 (212)

Complementary networks of cortical somatostatin interneurons enforce layer specific control

eLife, 2019
The neocortex is functionally organized into layers. Layer four receives the densest bottom up sensory inputs, while layers 2/3 and 5 receive top down inputs that may convey predictive information.
Alexander Naka, Julia Veit, Ben Shababo, Rebecca K Chance, Davide Risso, David Stafford, Benjamin Snyder, Andrew Egladyous, Desiree Chu, Savitha Sridharan, Daniel P Mossing, Liam Paninski, John Ngai, Hillel Adesnik   +13 more
doaj   +1 more source

Treatment challenges in and outside a specialist network setting: Pancreatic neuroendocrine tumours [PDF]

, 2019
Pancreatic Neuroendocrine Neoplasms comprise a group of rare tumours with special biology, an often indolent behaviour and particular diagnostic and therapeutic requirements.
Almar E., Arveux P., Autelitano M., Baldi I., Bara S., Barchielli A., Benfatto L., Benhamou E., Bento M. J., Bielska-Lasota M., Blaszczyk J., Bordoni A., Botta L., Bouchardy C., Bouvier A. -M., Bouvier V., Brewster D. H., Calleja N., Candela P., Caplin M., Capocaccia R., Carulla M., Clough-Gorr K., Colonna M., Comber H., De Angelis R., de Lacerda G. F., de Munain A. L., Diaz Garcia J. M., Diba C. S., Dimitrova N., Dusek L., Engel J., Ess S. M., Falcini F., Falconi M., Ferretti S., Filiberti R. A., Fusai G. K., Fusco M., Galceran J., Gatta G., Gavin A., Gennaro V., Gentilini M., Giacomin A., Gozdz S., Grosclaude P., Guizard A. -V., Hackl M., Heidrich J., Henau K., Holleczek B., Huws D. W., Iannelli A., Johannesen T. B., Jonasson J. G., Kepska K., Knijn A., Konzelmann I., Kunkler I., Lapotre-Ledoux B., Larranaga N., Leinonen M., Luttmann S., Lykoudis P. M., Madeddu A., Magi M., Malila N., Mallone S., Mangone L., Marani E., Marcos-Gragera R., Maspero S., Maynadie M., Mazzoleni G., Michiara M., Miranda A., Molinie F., Monnereau A., Moreno-Iribas C., Mousavi M., Muffatti F., Navarro C., Nennecke A., Pannozzo F., Partelli S., Pierannunzio D., Piffer S., Pildava S., Primic-Zakelj M., Rachtan J., Rashbass J., Ricci P., Robaszkiewicz M., Rossi S., Rugge M., Salmeron D., Sanchez M. J., Santaquilani M., Sardo A. S., Schubert-Fritschle G., Schvartz C., Sekerija M., Sensi F., Serraino D., Smailyte G., Spagnoli G., Stabenow R., Stracci F., Tagliabue G., Tavilla A., Torrella-Ramos A., Trama A., Tretarre B., Troussard X., Tumino R., Usala M., Van Eycken E., Velten M., Visser O., Vitale F., Woronoff A. -S., Ziino A.   +123 more
core   +1 more source

Alterations in hippocampal somatostatin interneurons, GABAergic metabolism, and ASL perfusion in an aged male mouse model of POCD aggravated by sleep fragmentation

Physiological Reports
Sleep fragmentation (SF) is increasingly recognized as a contributing factor to postoperative cognitive dysfunction (POCD). Given the critical roles of somatostatin (SST) interneurons, associated gamma‐aminobutyric acid (GABA)ergic neurotransmitters, and
Yun Li, Jiafeng Yu, Ningzhi Yang, Siwen Long, Yize Li, Lina Zhao, Yonghao Yu   +6 more
doaj   +1 more source

Somatostatin and cancer

Metabolism, 1996
The potential role of somatostatin (SRIF) in the diagnosis and treatment of nonendocrine human cancers is reviewed. There have been many reports of the growth-inhibitory activity of SRIF on normal and transformed cells in vitro. Many processes involved in malignant tumor growth depend on autocrine growth mechanisms, and somatostatin receptors (ssts ...
openaire   +2 more sources

Totalsynthese von Somatostatin-28 (Big-Somatostatin) / Total Synthesis of Somatostatin-28 (Big Somatostatin)

Zeitschrift für Naturforschung B, 1980
The total synthesis of the octacosapeptide corresponding to the proposed primary structure of porcine somatostatin-28, a possible precursor of somatostatin, is described. The primary structure of somatostatin-28 corresponds to that of somatostatin elongated at the N-terminus by a tetradecapeptide sequence.
E. Wünsch, L. Moroder, M. Gemeiner, E. Jaeger, A. Ribet, L. Pradayrol, N. Vaysse   +6 more
openaire   +1 more source

Intraoperative carcinoid syndrome during small-bowel neuroendocrine tumour surgery

Endocrine Connections, 2018
Only few descriptions of intraoperative carcinoid syndrome (ioCS) have been reported. The primary objective of this study was to describe ioCS. A second aim was to identify risk factors of ioCS.
Myrtille Fouché, Yves Bouffard, Mary-Charlotte Le Goff, Johanne Prothet, François Malavieille, Pierre Sagnard, Françoise Christin, Davy Hayi-Slayman, Arnaud Pasquer, Gilles Poncet, Thomas Walter, Thomas Rimmelé   +11 more
doaj   +1 more source

Local axonal morphology guides the topography of interneuron myelination in mouse and human neocortex

eLife, 2019
GABAergic fast-spiking parvalbumin-positive (PV) interneurons are frequently myelinated in the cerebral cortex. However, the factors governing the topography of cortical interneuron myelination remain incompletely understood.
Jeffrey Stedehouder, Demi Brizee, Johan A Slotman, Maria Pascual-Garcia, Megan L Leyrer, Bibi LJ Bouwen, Clemens MF Dirven, Zhenyu Gao, David M Berson, Adriaan B Houtsmuller, Steven A Kushner   +10 more
doaj   +1 more source

Somatostatin radioimmunoassay with 125I-N.ALPHA.-tyrosyl-somatostatin.

Endocrinologia Japonica, 1978
Nalpha-Tyrosyl-somatostatin was synthesized and proved to be homogeneous. Radioiodination of this tyrosine-containing somatostatin analogue by either the lactoperoxidase method or the chloramine T method led to the formation of crude iodinated compound, which was purified by ion exchange chromatography on CM-Sephadex C-25 using a linear ammonium ...
N, Yanaihara, H, Sato, N, Sakura, C, Yanaihara   +3 more
openaire   +3 more sources

La somatostatina en el núcleo del tracto solitario comisural modula la retención de glucosa cerebral postestimulación anóxica de los quimioreceptores carotídeos en ratas Somatostatin into the Commissural Nucleus Tractus Solitarius Modulates Brain Glucose Retention Post- Anoxic Stimulation of the Carotid Chemoreceptor in Rats

Revista Cubana de Investigaciones Biomédicas, 2013
El núcleo del tracto solitario comisural (NTSc) es el centro de relevo de las fibras aferentes procedentes de los baro y quimiorreceptores carotídeos, por lo que modula la presión arterial y la glucemia ante los estímulos en dichos receptores.
Sergio Adrián Montero Cruz, Mónica Lemus Vidal, José Francisco Figueroa Andrade, Christian Edgar Ceja Pelayo, Pablo Morales Hernández, José Alberto Pacheco Elizalde, José Luis Cadenas Freixas, Elena Roces Dorronsoro   +7 more
doaj  

Evaluation of the VP22 gene adjuvant for enhancement of DNA vaccine against somatostatin in mice

Animal, 2008
Somatostatin (SS) is a hormone that inhibits the secretion of growth hormone. Immunization against SS can promote the growth of animals. A novel SS-VP22 fused vaccine, pEGS2SS-V, was constructed from pEGS2SS plasmid with a VP22 gene fragment.
Li. Han, A.X. Liang, J. Zhang, M. Fang, G.H. Hua, L. Sang, L.Y. Geng, H.R. Wang, L.G. Yang   +8 more
doaj   +1 more source