Results 71 to 80 of about 76,206 (274)

Cortical GABAergic Dysfunction in Stress and Depression: New Insights for Therapeutic Interventions

Frontiers in Cellular Neuroscience, 2019
Major depressive disorder (MDD) is a debilitating illness characterized by neuroanatomical and functional alterations in limbic structures, notably the prefrontal cortex (PFC), that can be precipitated by exposure to chronic stress.
Manoela V. Fogaça, Ronald S. Duman
doaj   +1 more source

Goofy/123Cre lineage tracing differentiates olfactory and vomeronasal neurons from GnRH‐1 and terminal nerve neurons during neuronal migration and reveals additional olfactory placode‐derived cells in the brain

Developmental Dynamics, EarlyView.
Abstract The olfactory placode (OP) generates a broad array of chemosensory neurons in the nasal region, including olfactory sensory neurons, vomeronasal sensory neurons, neurons of the septal organ, and Grueneberg ganglion. During invagination, the OP also generates migratory neuronal populations, including gonadotropin‐releasing hormone‐1 (GnRH‐1 ...
Enrico Amato Jr., Mia V. Call, Noah M. LeFever, Mya Aviles‐Carlos, Nikki M. Dolphin, Paolo E. Forni   +5 more
wiley   +1 more source

Crosstalk of TGF-β and somatostatin signaling in adenocarcinoma and neuroendocrine tumors of the pancreas: a brief review

Frontiers in Endocrinology
Although the vast majority of cancers affecting the human pancreas are pancreatic ductal adenocarcinomas (PDAC), there are several other cancer types originating from non-exocrine cells of this organ, i.e., pancreatic neuroendocrine tumors (panNET ...
Hendrik Ungefroren, Hendrik Ungefroren, Harpal Randeva, Hendrik Lehnert, Jörg Schrader, Jens-Uwe Marquardt, Björn Konukiewitz, Ralf Hass   +7 more
doaj   +1 more source

No mortality difference following treatment with terlipressin or somatostatin in cirrhotic patients with gastric variceal hemorrhage

The Saudi Journal of Gastroenterology, 2016
Background/Aims: The aim of this study was to compare the efficacy of terlipressin versus somatostatin as adjuvants to endoscopic treatment in cirrhotic patients with gastric variceal bleeding. Patients and Methods: The National Health Insurance Database,
Tsung-Hsing Hung, Chen-Chi Tsai, guo-Chih TsenK, Yu-Hsi Hsieh, Chih-Wei Tseng   +4 more
doaj   +1 more source

CaMKIIβ insufficiency disrupts cortical networks, producing aberrant low‐gamma oscillations and seizure susceptibility

Epilepsia, EarlyView.
Abstract Objective Pathogenic variants in the calcium/calmodulin‐dependent protein kinase II B gene (CAMK2B) have been associated with neurodevelopmental disorders, including epilepsy, yet the mechanisms underlying cortical dysfunction remain largely unclear.
Hiroki Mutoh, Kazushi Aoto, Atsuo Fukuda, Hirotomo Saitsu   +3 more
wiley   +1 more source

PET of somatostatin receptor-positive tumors using 64Cu- and 68Ga-somatostatin antagonists: the chelate makes the difference

, 2011
Somatostatin-based radiolabeled peptides have been successfully introduced into the clinic for targeted imaging and radionuclide therapy of somatostatin receptor (sst)-positive tumors, especially of subtype 2 (sst2).
Keelara Abiraj, Mansi, Rosalba, Cescato, Renzo, Melpomeni Fani, Wolfgang A. Weber, Tamma, Maria Luisa, Waser, Beatrice, Helmut R. Maecke, Maecke, Helmut R, Reubi, Jean-Claude, Maria Luisa Tamma, Del Pozzo, Luigi, Luigi Del Pozzo, Rosalba Mansi, Fani, Melpomeni, Abiraj, Keelara, Beatrice Waser, Renzo Cescato, Jean Claude Reubi, Weber, Wolfgang A   +19 more
core   +1 more source

Effect of Bacillus cereus PAS38 and mannosan preparation on immunoreactive cells of somatostatin and 5-HT in small intestine of rabbit

浙江大学学报. 农业与生命科学版, 2009
Sixty male weaned rabbits were randomly divided into four groups: control group was fed the basic diet; PAS38 group was fed diet supplemented with 0.1% B.
PAN Kang-cheng, CHEN Zheng-li, CUI Heng-min, YUAN Chao-fu, CHEN Gang   +4 more
doaj   +1 more source

Anterior cingulate cortex neuron subtypes differentially regulate seizures

Epilepsia, EarlyView.
Abstract Objective This study aimed to investigate the regulatory roles of distinct neuronal subtypes within the anterior cingulate cortex (ACC) in acute seizures and to identify cell type‐specific mechanisms underlying seizure modulation in this region. Methods Acute seizure models were established in mice via pentylenetetrazol injection.
Ziqian Yan, Ting Tang, Kaishan Wang, Bin Fu, Zesheng Li, Mingshan Liu, Hongyi Huang, Yanfeng Yang, Qiang Zheng, Yangmin Zheng, Yongzhi Shan, Yumin Luo, Guoguang Zhao   +12 more
wiley   +1 more source

Mechanisms regulating somatostatin release and somatostatin-induced acetylcholine release from the myenteric plexus [PDF]

, 1990
The present studies were performed to characterize the molecular form(s) of somatostatin present in the myenteric plexus and to examine some aspects of the regulatory mechanisms underlying somatostatin release and somatostatin-induced release of ...
Owyang, Chung, Wiley, John, Yuanxu Lu,
core   +1 more source

Diagnostic accuracy of technetium-99m-octreotide in imaging neuroendocrine tumors, Oman hospital experience with literature review

World Journal of Nuclear Medicine, 2019
The aim of this observational cross-sectional study with retrospective review of the data is to evaluate the efficacy of using technetium-99m-octreotide (Tc-99m-OCT) in imaging neuroendocrine tumors (NETs) in our tertiary care hospital.
Naima Al Bulushi, Badriya Al Suqri, Marwa Al Aamri, Aymen Al Hadidi, Hafidh Al Jahdami, Mohammed Al Zadjali, Mimouna Al Risi   +6 more
doaj   +1 more source