Results 171 to 180 of about 128,394 (306)

Toward Personalized Stationary Chromatography Phases: Equipping Commercial Silica Phases with Selected Peptide‐Based Binding Domains to Tailor Affinity

open access: yesAdvanced Materials Interfaces, Volume 12, Issue 11, June 9, 2025.
The 7‐mer peptide motifs QFFLFFQ, QFFEFFQ, and QFQQSFF, known as good, medium, and poor binders for the photosensitizers m‐THPC and Chlorin E6 are covalently immobilized on commercial amino‐functionalized silica particles by inverse electron‐demand Diels‐Alder ligation.
Steffen A. Busche   +5 more
wiley   +1 more source

TP53 ‐Mutated Myeloid Neoplasms: 2024 Update on Diagnosis, Risk‐Stratification, and Management

open access: yesAmerican Journal of Hematology, Volume 100, Issue S4, Page 88-115, June 2025.
ABSTRACT Alterations in the tumor suppressor gene TP53 are common in human cancers and are associated with an aggressive nature. Approximately 8%–12% of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) harbor TP53 mutations (TP53 mut) and present immense challenges due to inherent chemoresistance and poor outcomes.
Mithun Vinod Shah   +2 more
wiley   +1 more source

Calcineurin controls the expression of numerous genes in cerebellar granule cells [PDF]

open access: yes, 2003
Ashby, Dominique S   +4 more
core   +1 more source

Nonsense Mutations in Rare and Ultra‐Rare Human Disorders: An Overview

open access: yesIUBMB Life, Volume 77, Issue 6, June 2025.
ABSTRACT Over 7000 rare diseases have been described, collectively affecting 350 million people worldwide. Most of these conditions result from nonsense mutations, representing approximately 10% of all genetic mutations associated with human inherited diseases.
Emanuele Vitale   +8 more
wiley   +1 more source

Clinicopathological Correlates of Hormone Expression-Based Subtypes of Non-Functioning Duodenal/Ampullary Neuroendocrine Tumors: A Multicenter Study of 151 Cases. [PDF]

open access: yesEndocr Pathol
Vanoli A   +24 more
europepmc   +1 more source

Candidate Anxiety‐Related Genes in the Hippocampus of Hatano Male Rats: Anxiolytic Action of Neuromedin U in the Hippocampus

open access: yesNeuropsychopharmacology Reports, Volume 45, Issue 2, June 2025.
We screened for gene candidates in the hippocampus related to anxiety using Hatano high avoidance animals (HAA) and low avoidance animals (LAA), inbred rat strains that exhibit high and low levels of anxiety‐like behavior. The microarray analysis revealed differences in 498 gene expressions between HAA and LAA, of which nine genes conducted RT‐qPCR ...
Kaito Sato   +11 more
wiley   +1 more source

The Role of Somatostatin in the Gastrointestinal Tract. [PDF]

open access: yesBiology (Basel)
Papantoniou K   +3 more
europepmc   +1 more source

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