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Cytochrome P450 1a (CYP1A)-Knockout Javanese Medaka Fish Exhibit Diabetic Traits and Reduced Reproductive Capacity. [PDF]

FASEB J
Rusni S, Yoshioka Y, Pratiwi HM, Takagi T, Royan MR, Hojo Y, Uno S, Kanda S, Takehana Y, Kinoshita M, Inoue K.   +10 more
europepmc   +1 more source

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Somatostatin-28, somatostatin-14 and somatostatin analogs: Effects on thermoregulation

Brain Research, 1981
Somatostatins, somatostatin-14, somatostatin-28, and desAA [D-Trp8]-somatostatin, with differential potencies, act in the brain to reverse chemical-induced hypothermia and to produce hyperthermia. Somatostatins are more potent and loger acting than prostaglandin E2 in producing hyperthermia.
Marvin R Brown
exaly   +3 more sources

Somatostatin and Somatostatin Receptors

2009
The biological effects of somatostatin (SST) were first encountered unexpectedly in the late 1960s in two unrelated studies, one by Krulich et al. (1968) who reported on a growth hormone (GH)-releasing inhibitory substance from hypothalamic extracts, and the other, by Hellman and Lernmark (1969), on the presence of a potent insulin inhibitory factor ...
Ujendra, Kumar, Michael, Grant
openaire   +2 more sources

Somatostatin and somatostatin analogues in oncology

Cancer Treatment Reviews, 1989
La somatostatine, et ses analogues, sa structure, sa pharmacologie, son effet antiproliferatif, et son activite anticancereux sont ...
H, Parmar, A, Bogden, M, Mollard, B, de Rougé, R H, Phillips, S L, Lightman   +5 more
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Evolutionary history of the somatostatin and somatostatin receptors

Journal of Genetics, 2009
Somatostatin and its receptors have a critical role in mammalian growth through their control pattern of secretion of growth hormone, but the evolutionary history of somatostatin and somatostatin receptors are ill defined. We used comparative whole genome analysis of Danio rerio, Carassius auratus, Xenopus tropicalis, Gallus gallus, Monodelphis ...
Muhammad, Moaeen-ud-Din, Li Guo, Yang
openaire   +2 more sources

Somatostatin Analogs Inhibit Somatostatin Release*

Endocrinology, 1979
To determine if, like insulin, somatostatin inhibits its own secretion from the pancreas, nonimmunoreactive analogs of somatostatin were perfused in an isolated dog pancreaticoduodenal preparation using a nonrecirculating system. [D-Trp8-D-Cys14]somatostatin, at a concentration of 200 ng/ml, blocked the response of somatostatin-like immunoreactivity ...
E, Ipp, J, Rivier, R E, Dobbs, M, Brown, W, Vale, R H, Unger   +5 more
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Somatostatin and somatostatin receptors in fish growth

General and Comparative Endocrinology, 2010
Multiple forms of somatostatin (SS) and SS receptors (SSTR) are produced widely in the tissues of fish and interact to coordinate numerous physiological processes. Insight into their role in growth regulation emerged from studies of abnormal growth and of whole animals.
Mark A, Sheridan, Alison L, Hagemeister
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Somatostatin

Cellular and Molecular Neurobiology, 1995
1. Somatostatin (SRIF) exerts diverse physiological actions in the body including regulation of hormone and neurotransmitter release and neuronal firing activity. Analogs of SRIF are used clinically to treat tumors and cancers and to block the hypersecretion of growth hormone in acromegaly. 2.
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