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Somatostatin-28, somatostatin-14 and somatostatin analogs: Effects on thermoregulation

Brain Research, 1981
Somatostatins, somatostatin-14, somatostatin-28, and desAA [D-Trp8]-somatostatin, with differential potencies, act in the brain to reverse chemical-induced hypothermia and to produce hyperthermia. Somatostatins are more potent and loger acting than prostaglandin E2 in producing hyperthermia.
Marvin Brown, N Ling, Nicholas Ling
exaly   +3 more sources

Somatostatin and Somatostatin Receptors

2009
The biological effects of somatostatin (SST) were first encountered unexpectedly in the late 1960s in two unrelated studies, one by Krulich et al. (1968) who reported on a growth hormone (GH)-releasing inhibitory substance from hypothalamic extracts, and the other, by Hellman and Lernmark (1969), on the presence of a potent insulin inhibitory factor ...
Ujendra, Kumar, Michael, Grant
openaire   +2 more sources

Somatostatin and somatostatin analogues in oncology

Cancer Treatment Reviews, 1989
La somatostatine, et ses analogues, sa structure, sa pharmacologie, son effet antiproliferatif, et son activite anticancereux sont ...
H, Parmar   +5 more
openaire   +2 more sources

Somatostatin Analogs Inhibit Somatostatin Release*

Endocrinology, 1979
To determine if, like insulin, somatostatin inhibits its own secretion from the pancreas, nonimmunoreactive analogs of somatostatin were perfused in an isolated dog pancreaticoduodenal preparation using a nonrecirculating system. [D-Trp8-D-Cys14]somatostatin, at a concentration of 200 ng/ml, blocked the response of somatostatin-like immunoreactivity ...
E, Ipp   +5 more
openaire   +2 more sources

Somatostatin, Somatostatin Receptors, and Pancreatic Cancer

World Journal of Surgery, 2005
AbstractSomatostatin may play an important role in the regulation of cancer growth including pancreatic cancer by interaction with somatostatin receptors (SSTRs) on the cell surface. Five SSTRs were cloned, and the function of these SSTRs is addressed in this review.
Min, Li   +6 more
openaire   +2 more sources

Evolutionary history of the somatostatin and somatostatin receptors

Journal of Genetics, 2009
Somatostatin and its receptors have a critical role in mammalian growth through their control pattern of secretion of growth hormone, but the evolutionary history of somatostatin and somatostatin receptors are ill defined. We used comparative whole genome analysis of Danio rerio, Carassius auratus, Xenopus tropicalis, Gallus gallus, Monodelphis ...
Muhammad, Moaeen-ud-Din, Li Guo, Yang
openaire   +2 more sources

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