Results 201 to 210 of about 57,549 (242)
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Trends in Endocrinology and Metabolism, 1985
It is now well established that the biological actions of tetradecapeptide somatostatin (somatostatin-14, S-14) are receptor-mediated. These receptors were first quantified in GH4C pituitary tumor cells using [125I-Tyr1] S-14 as radioligand which was found to exhibit high non-specific binding to membrane receptor preparations from normal tissues.
Y C, Patel, C B, Srikant
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It is now well established that the biological actions of tetradecapeptide somatostatin (somatostatin-14, S-14) are receptor-mediated. These receptors were first quantified in GH4C pituitary tumor cells using [125I-Tyr1] S-14 as radioligand which was found to exhibit high non-specific binding to membrane receptor preparations from normal tissues.
Y C, Patel, C B, Srikant
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Hormone Research, 2008
Biological activity of somatostatin can be altered by modiñcations in the amino acid sequence. Thus, a number of bioassays have been developed in order to measure the potency and specificity of analogues and heterogenous molecular forms of somatostatin.
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Biological activity of somatostatin can be altered by modiñcations in the amino acid sequence. Thus, a number of bioassays have been developed in order to measure the potency and specificity of analogues and heterogenous molecular forms of somatostatin.
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Journal of Endocrinological Investigation, 2003
We discuss the recent knowledge concerning domatostatin action in follicular and parafollicular cell function regulation.
ZATELLI, Maria Chiara +2 more
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We discuss the recent knowledge concerning domatostatin action in follicular and parafollicular cell function regulation.
ZATELLI, Maria Chiara +2 more
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Disease-a-Month, 1978
The islets of Langerhans contain at least four major cell types—the A, A2, or α cell; the B or β cell; the D or A1 cell; and the F cell—containing, respectively, glucagon, insulin, somatostatin, and pancreatic polypeptide. In every species thus far examined, these four cell types bear a constant topographical relationship to one another, although the ...
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The islets of Langerhans contain at least four major cell types—the A, A2, or α cell; the B or β cell; the D or A1 cell; and the F cell—containing, respectively, glucagon, insulin, somatostatin, and pancreatic polypeptide. In every species thus far examined, these four cell types bear a constant topographical relationship to one another, although the ...
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Scandinavian Journal of Gastroenterology, 1986
More insight into the biochemical structure and operation of the somatostatin receptor(s) has been gained in recent years from several approaches. The minimal active structure of the receptor(s) has been identified, and active minisomatostatins have been synthesized.
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More insight into the biochemical structure and operation of the somatostatin receptor(s) has been gained in recent years from several approaches. The minimal active structure of the receptor(s) has been identified, and active minisomatostatins have been synthesized.
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American Journal of Physiology-Gastrointestinal and Liver Physiology, 1995
Somatostatin induces its biological actions by activating a family of receptor subtypes. The recent cloning of five somatostatin receptor subtypes has led to the development of subtype-selective agonists. These compounds are revealing distinct functions of the individual receptor subtypes.
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Somatostatin induces its biological actions by activating a family of receptor subtypes. The recent cloning of five somatostatin receptor subtypes has led to the development of subtype-selective agonists. These compounds are revealing distinct functions of the individual receptor subtypes.
openaire +2 more sources