Results 221 to 230 of about 84,280 (274)
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Current Molecular Medicine, 2013
The pharmacological effects (i.e., inhibition of endocrine secretion and cell proliferation) mediated by the hormone somatostatin (SRIF) are derived from its universal high-affinity binding to five different G proteincoupled receptors (GPCRs), named sst1-5.
Ruscica M +4 more
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The pharmacological effects (i.e., inhibition of endocrine secretion and cell proliferation) mediated by the hormone somatostatin (SRIF) are derived from its universal high-affinity binding to five different G proteincoupled receptors (GPCRs), named sst1-5.
Ruscica M +4 more
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Cellular and Molecular Neurobiology, 1995
1. Somatostatin (SRIF) exerts diverse physiological actions in the body including regulation of hormone and neurotransmitter release and neuronal firing activity. Analogs of SRIF are used clinically to treat tumors and cancers and to block the hypersecretion of growth hormone in acromegaly. 2.
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1. Somatostatin (SRIF) exerts diverse physiological actions in the body including regulation of hormone and neurotransmitter release and neuronal firing activity. Analogs of SRIF are used clinically to treat tumors and cancers and to block the hypersecretion of growth hormone in acromegaly. 2.
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Somatostatin and somatostatin receptors in fish growth
General and Comparative Endocrinology, 2010Multiple forms of somatostatin (SS) and SS receptors (SSTR) are produced widely in the tissues of fish and interact to coordinate numerous physiological processes. Insight into their role in growth regulation emerged from studies of abnormal growth and of whole animals.
Mark A, Sheridan, Alison L, Hagemeister
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Somatostatin and Somatostatin Receptor Physiology
Endocrine, 2003Since the discovery of somatostatin (SST) over three decades ago, its ubiquitous distribution and manifold functions are still being documented. SST is synthesized in the hypothalamus and transported to the anterior pituitary gland where it tonicaly inhibits GH and TSH secretion as well as being responsible for GH pulsatile release.
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Somatostatin analogues: Are they analogues of somatostatin?
Journal of Endocrinological Investigation, 2002Dear Sir, Somatostatin (SRIH) was discovered because of its surprising inhibitory effect on GH secretion (1), and thus appropriately named. Later on, its ubiquitousness and the inhibiting activity on pancreatic hormones and on other types of hormones, rendered its name too restrictive. It was by then too late to change it.
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Lung Cancer, 1993
Lung carcinoma is the most common cause of death in the western world and is increasing particularly among women. Despite significant developments in our understanding of the molecular biology of this disease our ability to treat the various subtypes of lung cancer has been at a relative standstill for the past decade.
K J, O'Byrne, D N, Carney
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Lung carcinoma is the most common cause of death in the western world and is increasing particularly among women. Despite significant developments in our understanding of the molecular biology of this disease our ability to treat the various subtypes of lung cancer has been at a relative standstill for the past decade.
K J, O'Byrne, D N, Carney
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The Journal of Peptide Research, 2001
Abstract: Somatostatin is a hypothalamic peptide hormone that inhibits the secretion of growth hormone, glucagon, insulin, gastrin and secretin, and also plays a role in neural transmission. Because of its wide range of possible clinical applications hundreds of somatostatin analogs have been synthesized and bioassayed to date.
A, Janecka, M, Zubrzycka, T, Janecki
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Abstract: Somatostatin is a hypothalamic peptide hormone that inhibits the secretion of growth hormone, glucagon, insulin, gastrin and secretin, and also plays a role in neural transmission. Because of its wide range of possible clinical applications hundreds of somatostatin analogs have been synthesized and bioassayed to date.
A, Janecka, M, Zubrzycka, T, Janecki
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Metabolism, 1990
Hippocampal neurons containing somatostatin have been shown to be vulnerable in some experimental models of epilepsy. In this report, we describe our recent findings about the seizure-related changes in somatostatin in brain tissue and cerebrospinal fluid (CSF) in experimental and human epilepsy.
P J, Riekkinen, A, Pitkänen
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Hippocampal neurons containing somatostatin have been shown to be vulnerable in some experimental models of epilepsy. In this report, we describe our recent findings about the seizure-related changes in somatostatin in brain tissue and cerebrospinal fluid (CSF) in experimental and human epilepsy.
P J, Riekkinen, A, Pitkänen
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Journal of Endocrinological Investigation, 2003
We discuss the recent knowledge concerning domatostatin action in follicular and parafollicular cell function regulation.
ZATELLI, Maria Chiara +2 more
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We discuss the recent knowledge concerning domatostatin action in follicular and parafollicular cell function regulation.
ZATELLI, Maria Chiara +2 more
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[Somatostatin and somatostatin receptors in the prostate].
Minerva endocrinologica, 2001Somatostatin (st) exerts a role in the control of prostate growth and function acting both at hypothalamus-hypophysis level and at glandular level. St analogues have been used to control prostate cancer (CaP) in clinical trials, with contradictory results.
SINISI, Antonio Agostino +2 more
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