Results 171 to 180 of about 117,172 (212)
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The Journal of Peptide Research, 2001
Abstract: Somatostatin is a hypothalamic peptide hormone that inhibits the secretion of growth hormone, glucagon, insulin, gastrin and secretin, and also plays a role in neural transmission. Because of its wide range of possible clinical applications hundreds of somatostatin analogs have been synthesized and bioassayed to date.
A, Janecka, M, Zubrzycka, T, Janecki
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Abstract: Somatostatin is a hypothalamic peptide hormone that inhibits the secretion of growth hormone, glucagon, insulin, gastrin and secretin, and also plays a role in neural transmission. Because of its wide range of possible clinical applications hundreds of somatostatin analogs have been synthesized and bioassayed to date.
A, Janecka, M, Zubrzycka, T, Janecki
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1985
This is a review of pancreatic somatostatin which is limited in its scope and therefore focuses upon some selected issues. Throughout the entire review the same basic questions recur: Why do islets contain somatostatin? What is the physiological role of somatostatin and what does this peptide have to do with diabetes?
G C, Weir, S, Bonner-Weir
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This is a review of pancreatic somatostatin which is limited in its scope and therefore focuses upon some selected issues. Throughout the entire review the same basic questions recur: Why do islets contain somatostatin? What is the physiological role of somatostatin and what does this peptide have to do with diabetes?
G C, Weir, S, Bonner-Weir
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[Somatostatin and somatostatin receptors in the prostate].
Minerva endocrinologica, 2001Somatostatin (st) exerts a role in the control of prostate growth and function acting both at hypothalamus-hypophysis level and at glandular level. St analogues have been used to control prostate cancer (CaP) in clinical trials, with contradictory results.
SINISI, Antonio Agostino +2 more
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Hormone Research, 1988
Biological activity of somatostatin can be altered by modifications in the amino acid sequence. Thus, a number of bioassays have been developed in order to measure the potency and specificity of analogues and heterogeneous molecular forms of somatostatin.
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Biological activity of somatostatin can be altered by modifications in the amino acid sequence. Thus, a number of bioassays have been developed in order to measure the potency and specificity of analogues and heterogeneous molecular forms of somatostatin.
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Journal of Endocrinological Investigation, 2003
We discuss the recent knowledge concerning domatostatin action in follicular and parafollicular cell function regulation.
ZATELLI, Maria Chiara +2 more
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We discuss the recent knowledge concerning domatostatin action in follicular and parafollicular cell function regulation.
ZATELLI, Maria Chiara +2 more
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Medical Clinics of North America, 1978
Somatostatin may act as a local regulator of endocrine and exocrine secretion and as a peptidergic neurotransmitter rather than as a classical circulating hormone. The possible physiologic role of its secretion in the regulation of islet A and B cell function, and particularly its significance in nutrient homeostasis and diabetes, are discussed.
R A, Rizza, J E, Gerich
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Somatostatin may act as a local regulator of endocrine and exocrine secretion and as a peptidergic neurotransmitter rather than as a classical circulating hormone. The possible physiologic role of its secretion in the regulation of islet A and B cell function, and particularly its significance in nutrient homeostasis and diabetes, are discussed.
R A, Rizza, J E, Gerich
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Disease-a-Month, 1978
The islets of Langerhans contain at least four major cell types—the A, A2, or α cell; the B or β cell; the D or A1 cell; and the F cell—containing, respectively, glucagon, insulin, somatostatin, and pancreatic polypeptide. In every species thus far examined, these four cell types bear a constant topographical relationship to one another, although the ...
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The islets of Langerhans contain at least four major cell types—the A, A2, or α cell; the B or β cell; the D or A1 cell; and the F cell—containing, respectively, glucagon, insulin, somatostatin, and pancreatic polypeptide. In every species thus far examined, these four cell types bear a constant topographical relationship to one another, although the ...
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Somatostatin and somatostatin receptors in the diagnosis and treatment of gliomas
Journal of Neuro-Oncology, 1997Somatostatin analogues are in clinical use for the diagnosis and treatment of several oncological indications, namely pituitary adenomas and endocrine gastrointestinal tumors. In addition for a variety of malignancies their potential value is being studied.
K, Lamszus, W, Meyerhof, M, Westphal
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