Results 141 to 150 of about 75,344 (257)
ABSTRACT The objective was to prepare guidelines to perform the current optimum treatment by organizing effective and efficient treatments of hemangiomas and vascular malformations, confirming the safety, and systematizing treatment, employing evidence‐based medicine techniques and aimed at improvement of the outcomes.
Yoshiaki Kinoshita +116 more
wiley +1 more source
Delta‐Cell Area is Unchanged in Human Pregnancy: Evidence From Immunohistochemistry
Pancreatic δ‐cell area is unchanged in human pregnancy despite well‐described expansion of α‐ and β‐cell populations. Using whole‐slide quantitative immunohistochemistry, we show that δ‐cell area and islet architecture remain stable, highlighting the selective nature of endocrine cell plasticity in the maternal pancreas. ABSTRACT Aim Pancreatic islet δ‐
Faheem Seedat +7 more
wiley +1 more source
Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos +16 more
wiley +1 more source
Review: “The Disappointment Dilemma: Short‐ and Long‐Term Learning From Negative Outcomes”
The habenula routes negative‐outcome signals to VTA, RMTg, and IPN to shape aversive learning and motivation. The lateral habenula encodes acute negative prediction errors to rapidly adapt behavior to threat, fear, and avoidance. The medial habenula integrates repeated stress, drug, and aversive experiences into long‐term negative mood and expectations.
Ines Ibañez‐Tallon +4 more
wiley +1 more source
Abstract Ki‐67 index and mitotic count form the basis of grading of small intestinal neuroendocrine tumours (siNET). We hypothesized that the mitosis‐specific marker phosphohistone H3 (PHH3) might better correlate with cancer‐specific survival (CSS) and with response to treatment. We evaluated the association between Ki‐67 index, PHH3‐estimated mitotic
Dimitrios Papantoniou +2 more
wiley +1 more source
Somatostatin receptor PET in meningioma: diagnosis, therapy, and surveillance. [PDF]
Gujral J +9 more
europepmc +1 more source
Somatostatin Receptor Expression of Gastroenteropancreatic Neuroendocrine Tumors: A Comprehensive Analysis in the Era of Somatostatin Receptor PET Imaging. [PDF]
Maratta MG +6 more
europepmc +1 more source
Prolonged Somatostatin Receptor 2 Antagonism Enhances Glucagon Response to Hypoglycemia in Male Diabetic Rats. [PDF]
D'Souza NC +9 more
europepmc +1 more source
Somatostatin receptor PET-guided treatment and artificial intelligence applications in meningioma: a comprehensive review. [PDF]
Gujral J +7 more
europepmc +1 more source

