Results 101 to 110 of about 30,172 (220)

Amacrine cell inputs to OFF midget ganglion cells in macaque retina

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The goal of this study was to explain the findings from physiological studies that OFF midget ganglion cells had larger receptive field centers than expected from their dendritic field diameters. First, we confirmed that OFF mRGCs (OFF MGC) receive input from diffuse bipolar cells (DB) as well as OFF midget bipolar cells (FMB ...
David W. Marshak   +8 more
wiley   +1 more source

Endocrine and androgenic response to altitude training in professional cyclists

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Steroidal and endocrine variables are altered during altitude training. Abstract This study investigated endocrine and steroidal blood markers in 31 male elite cyclists monitored over 7 weeks, including a 3 week altitude training camp either at 2050 m (n = 19) or 3000 m (n = 12).
Raphael Faiss   +11 more
wiley   +1 more source

Somatostatin receptor scintigraphy with 68Ga-DOTATATE PET/CT: initial experience in Cuba

open access: yesNucleus, 2017
In 1870, Rudolf Heidenhain discovered neuroendocrine cells, which can lead to the development of the Neuroendocrine Tumors (NER), a rare form of cancer, most of which express somatostatin receptors.
Juan P. Oliva González
doaj  

Stathmin‐2 mediates paracrine hormone regulation of glucagon through lysosomal trafficking in αTC1‐6 cells

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Paracrine regulation of glucagon involves Stathmin2‐mediated trafficking of glucagon through lysosomal transport. Glucagon secretion is regulated by the paracrine hormones insulin and somatostatin. We postulate that insulin enhances lysosomal transport of glucagon away from sites of exocytosis, and somatostatin functions in the ...
Nelson Chang   +2 more
wiley   +1 more source

Frozen in Place: Proximity Labeling Maps Glial Interactomes Across Cell States

open access: yesGlia, Volume 74, Issue 10, October 2026.
Proximity labeling enables cell‐type‐specific and spatially resolved mapping of glial protein networks. Proximity labeling approaches provide insights into glial function under physiological and pathological conditions. ABSTRACT Glial cells, including radial glia, oligodendrocyte precursor cells (OPCs), oligodendrocytes, astrocytes, and microglia, are ...
João Baltar   +3 more
wiley   +1 more source

Structural insights into ligand recognition and selectivity of somatostatin receptors. [PDF]

open access: yesCell Res, 2022
Zhao W   +23 more
europepmc   +1 more source

Parvalbumin interneurons in Alzheimer's disease: Physiological insights and pathophysiological mechanisms

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Physiological and Pathological Alterations in PV+ Neurons: Under physiological conditions, PV+ interneurons exhibit fast‐spiking properties and generate gamma oscillations at the cost of high energy consumption. In AD, PV+ neurons display abnormalities in ion channels, dendrites, neurotransmission, energy metabolism, and neural oscillations, ultimately
Mengyan Wu   +5 more
wiley   +1 more source

Development of anti-somatostatin receptors CAR T cells for treatment of neuroendocrine tumors. [PDF]

open access: yesJ Immunother Cancer, 2022
Mandriani B   +11 more
europepmc   +1 more source

Tirzepatide and SGLT2 Inhibitors for Heart Failure With Preserved Ejection Fraction and Obesity: Entering a New Cardiometabolic Therapeutic Era

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
Tirzepatide and SGLT2 inhibitors act through distinct but complementary mechanisms in obesity‐related HFpEF: tirzepatide targets adiposity, inflammation, and insulin resistance, while SGLT2 inhibitors improve decongestion, myocardial energetics, and cardiac remodeling.
Zakariye Isak Mohamed   +8 more
wiley   +1 more source

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