Results 121 to 130 of about 31,554 (221)

Neuropathic Pain: From Mechanisms to Therapeutic Interventions

MedComm, Volume 7, Issue 10, October 2026.
Neuropathic pain arises from peripheral nerve injury, central sensitization, neurotransmitter imbalance, neuroimmune activation, and maladaptive circuit remodeling. Clinical phenotyping and multimodal imaging can identify dominant peripheral and central mechanisms.
Yaling Dai, Mengquan Tan, Man Yuan, Huixian Zhou, Qin Xie, Jiling Zeng, Yixin Yang, Xinran He, Siyuan Song   +8 more
wiley   +1 more source

Detection of acute myocarditis by ECG-triggered PET imaging of somatostatin receptors compared to cardiac magnetic resonance: preliminary results. [PDF]

J Nucl Cardiol, 2023
Boursier C, Chevalier E, Varlot J, Filippetti L, Huttin O, Roch V, Imbert L, Albuisson E, Claudin M, Mandry D, Marie PY.   +10 more
europepmc   +1 more source

Cross‐Talk Between Histamine H2 Receptor and Glucocorticoid Receptor: Potential Implications in Acute Myeloid Leukemia Treatment

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT This study investigates the impact of histamine H2 receptor activation on glucocorticoid receptor (GR)‐mediated transcriptional activity, as well as its effects on leukemic cell proliferation and chemotherapy resistance. We demonstrate that activation of the histamine H2 receptor by its specific agonist, amthamine, enhances GR transcriptional ...
Valeria Torralba‐Agu, Natalia Fernández, Carina Shayo, Carlos Davio, C. Daniel Zappia, Federico Monczor   +5 more
wiley   +1 more source

(+)‐Trans‐Cannabidiol Is an Agonist at Human CB2 Receptors

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT (−)‐trans‐Cannabidiol ((−)‐CBD) is a principal phytocannabinoid from Cannabis sativa. (−)‐CBD has complex pharmacology but is a relatively weak inhibitor of CB1 and CB2 receptor signaling. Cannabidiol has two chiral centres and thus four stereoisomers.
Pedro Bans Burtchaell, Marina Junqueira Santiago, Chenxi Wang, Mehdi Hagdoost, Evie J. M. Clay, Dani Mohnot, Mark Connor   +6 more
wiley   +1 more source

Concurrent Targeting of Vasopressin Receptor 2 and Somatostatin Receptors in Autosomal Dominant Polycystic Kidney Disease: A Promising Approach for Autosomal Dominant Polycystic Kidney Disease Treatment? [PDF]

Clin J Am Soc Nephrol, 2023
Hogan MC, Masyuk TV.
europepmc   +1 more source

Somatostatin receptors shape insulin and glucagon output within the pancreatic islet in mice through direct and paracrine effects. [PDF]

Diabetologia
Hart RG, Lee JJ, Zhai K, Lee S, Chauhan R, Hosseini A, Nguyen AD, Huising MO.   +7 more
europepmc   +1 more source

Small Bowel Cancer: Implications of Preoperative Work‐Up on Surgical Strategy

World Journal of Surgery, Volume 50, Issue 10, Page 3008-3019, October 2026.
Small bowel cancers comprise a heterogeneous group of malignancies, making diagnosis and treatment challenging. This study aimed to evaluate the ability of preoperative diagnostic work‐up to predict clinical and histopathological findings, facilitate subgroup identification, and support tailored, individualized surgical strategies. Preoperative work‐up
Erik Kjæstad, Espen Thiis‐Evensen, Anita Sveen, Arne Olav Bakka, Johannes Kurt Schultz   +4 more
wiley   +1 more source

Expression of ATRX, DAXX, PDX1, ARX, and somatostatin receptors in pancreatic neuroendocrine tumors: a clinicopathological study. [PDF]

Front Endocrinol (Lausanne)
Ciobanu OA, Martin CS, Fica S, Herlea V, Tudose I, Vasilescu F, Sandra I, Barbu CG.   +7 more
europepmc   +1 more source

Ga-68-Edotreotide Positron Emission Tomography/Computed Tomography Somatostatin Receptors Tumor Volume Predicts Outcome in Patients With Primary Gastroenteropancreatic Neuroendocrine Tumors. [PDF]

Cancer Control, 2023
Gallicchio R, Giordano A, Milella M, Storto R, Pellegrino T, Nardelli A, Nappi A, Tarricone L, Storto G.   +8 more
europepmc   +1 more source

Extended D3 Mesenterectomy in Small Bowel Cancer Treatment: Feasibility and Importance for Staging. First Results of a Prospective Clinical Trial

World Journal of Surgery, Volume 50, Issue 10, Page 2996-3007, October 2026.
There is no consensus on surgical techniques in small bowel cancer, particularly regarding the extent of lymph node dissection and strategic choices according to tumor localization and histological type. Clearance of central lymph node metastases can be challenging, especially when small intestinal neuroendocrine tumor (siNET) metastases give rise to ...
Erik Kjæstad, Espen Thiis‐Evensen, Bjørn Edwin, Arne Olav Bakka, Anne Helene Lilleaas, Yngve Thorsen, Johannes Kurt Schultz   +6 more
wiley   +1 more source