Results 141 to 150 of about 31,554 (221)

Impact of Osilodrostat on Health‐Related Quality of Life in Cushing's Disease: Analysis of Patient‐Reported Outcomes From the Phase III LINC 3 and LINC 4 Clinical Trials

open access: yesClinical Endocrinology, Volume 105, Issue 4, Page 452-463, October 2026.
ABSTRACT Objective Evaluate the effects of osilodrostat short‐ and long‐term treatment on health‐related quality of life (HRQoL) in Cushing's disease. Design LINC 3 and LINC 4 studies (pooled analysis). Patients 185 patients (mean baseline total scores: Cushing's Quality of Life [CushingQoL], 44.0; Beck Depression Inventory II [BDI‐II], 15.6; EuroQol ...
John Newell‐Price   +6 more
wiley   +1 more source

Small Bowel Lesions and Bleeding Risk in Hemodialysis Patients: A Narrative Review

open access: yesHemodialysis International, Volume 30, Issue 4, Page 665-678, October 2026.
ABSTRACT Background Gastrointestinal bleeding is very common among hemodialysis patients. This high bleeding risk is caused by uremic platelet dysfunction, vascular fragility, intradialytic hemodynamic instability, and widespread antithrombotic therapy.
Andreas Smyrlis   +3 more
wiley   +1 more source

Expression of somatostatin receptors in canine and feline meningioma. [PDF]

open access: yesVet Med Sci
Immler M   +6 more
europepmc   +1 more source

The Role of Kappa‐Opioid Receptor/Dynorphin System in Modulating Neural‐Circuits of Depression and Anxiety—A Review

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 19, October 2026.
ABSTRACT Major depression and anxiety disorders are psychiatric disorders that involve a great number of people. There is a growing need for new and better pharmacological treatments for these diseases. Kappa‐opioid receptor (KOR) antagonists seem to be a promising new pathway for the development of new antidepressants and anxiolytics, but a great ...
Cristian Ciotei   +8 more
wiley   +1 more source

Selective ligand recognition and activation of somatostatin receptors SSTR1 and SSTR3. [PDF]

open access: yesProc Natl Acad Sci U S A
Wang Y   +13 more
europepmc   +1 more source

Controversies in NEN: An ENETS position statement on the role of liver transplantation (LT) in patients with advanced small‐intestinal and pancreatic NETs

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract Liver transplantation (LT) may offer survival or symptomatic benefit for highly selected patients with advanced, well‐differentiated small‐intestinal or pancreatic neuroendocrine tumours and unresectable liver‐dominant metastases. However, its role remains controversial, as LT is rarely curative, recurrence is common, and benefits must be ...
Peter Stålberg   +11 more
wiley   +1 more source

Predictors of in vitro response to somatostatin and dopamine receptor‐targeted treatments are lacking in clinically non‐functioning pituitary tumors

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract Clinically non‐functioning pituitary neuroendocrine tumors (NF‐PitNETs) lack effective medical therapies, and the role of somatostatin receptor ligands (SRLs) and dopamine agonists (DAs) in this setting is controversial. We evaluated the in vitro response of NF‐PitNETs to multiple SRL and/or DA treatments, focusing on the role of receptor ...
Claudia Campana   +9 more
wiley   +1 more source

Corrigendum: Estrogens modulate somatostatin receptors expression and synergize with the somatostatin analog pasireotide in prostate cells. [PDF]

open access: yesFront Pharmacol
Rossi V   +8 more
europepmc   +1 more source

Types of Neurons in the Myenteric Plexus of Human Gastric Corpus Identified by Multi‐Layer Immunohistochemical Coding and Vagal Tracing

open access: yesNeurogastroenterology &Motility, Volume 38, Issue 10, October 2026.
Myenteric nerve cell bodies in the human gastric corpus were divided into 12 classes by the combinatorial expression of 15 neuronal markers, using multiplexed immunohistochemistry (1084 neurons from 7 individuals). Baskets of axonal varicosities from vagal or enteric sources were analyzed to detect targeted patterns of connectivity ...
M. E. Johnson   +10 more
wiley   +1 more source

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