Results 151 to 160 of about 66,215 (305)

Supplementary Figures S1-S5 from Network Modeling of TGFβ Signaling in Hepatocellular Carcinoma Epithelial-to-Mesenchymal Transition Reveals Joint Sonic Hedgehog and Wnt Pathway Activation

, 2023
Steven N. Steinway, Jorge Gómez Tejeda Zañudo, Wei Ding, Carl Bart Rountree, David J. Feith, Thomas P. Loughran, Réka Albert   +6 more
openalex   +1 more source

Sonic hedgehog [PDF]

Current Biology, 1998
openaire   +2 more sources

The role of vitamin D receptor signaling in hair follicle health and alopecia: Current understanding and therapeutic implications

Journal of Cell Communication and Signaling, Volume 20, Issue 1, March 2026.
The vitamin D receptor (VDR) regulates hair follicle biology through ligand‐dependent and ligand‐independent mechanisms by heterodimerizing with retinoid X receptor, recruiting coactivator complexes, and activating target genes including Wnt inhibitors, hair keratins, and cell cycle regulators.
Liancheng Guan, Fan Yang, Meijuan Li, Yujia Chen, Zexin Zhao, Hongxia Li, Deping Luo, Qian Li, Yunzhi Chen   +8 more
wiley   +1 more source

Data from Overexpression of Smoothened Activates the Sonic Hedgehog Signaling Pathway in Pancreatic Cancer–Associated Fibroblasts

, 2023
Kimberly Walter, Noriyuki Omura, Seung‐Mo Hong, Margaret Griffith, Audrey Vincent, Michael Borges, Michael Goggins   +6 more
openalex   +1 more source

A subpopulation of astrocyte progenitors defined by Sonic hedgehog signaling [PDF]

, 2022
Ellen C. Gingrich, Kendra Case, A. Denise R. Garcia   +2 more
openalex   +1 more source

Sonic hedgehog

Molecular Pathology, 2003
H S, Heussler, M, Suri
openaire   +3 more sources

Unconventional Secretion of Angiogenic Sonic Hedgehog–Containing Extra‐Large Extracellular Vesicles is Driven by PI3K–Rab18‐GDP Signalling

Journal of Extracellular Biology, Volume 5, Issue 2, February 2026.
Human mesenchymal stem cells conditionally secrete sonic hedgehog (SHH)‐containing extra‐large extracellular vesicles (XLEVs) upon PI3K activation, which enriches the GDP‐bound form of Rab18. Rab18‐GDP drives perinuclear maturation and polarized vertical release of SHH‐XLEVs via Hsp90α‐ and nSMase2‐dependent mechanisms.
Shuo Wang, Rio Imai, Yuya Kaneko, Yosuke Tanaka   +3 more
wiley   +1 more source

Supplementary Figures from Sonic Hedgehog Signaling Drives Mitochondrial Fragmentation by Suppressing Mitofusins in Cerebellar Granule Neuron Precursors and Medulloblastoma

, 2023
Anshu Malhotra, Abhinav Dey, Niyathi Prasad, Anna Marie Kenney   +3 more
openalex   +1 more source

Missense Variants in the Second Transmembrane Domain of TMEM17 Disrupt Its Stability and Function and Lead to a Wide Phenotypic Spectrum of Ciliopathies

Clinical Genetics, Volume 109, Issue 2, Page 305-315, February 2026.
Missense variants in TMEM17 disrupt its localization and function at the ciliary transition zone, leading to a wide range of ciliopathy phenotypes, from OFD6 and Joubert syndromes to Meckel syndrome. ABSTRACT Ciliopathies are rare genetic disorders characterized by significant genetic and phenotypic variability.
Lucile Boutaud, Chunmei Li, Candice Moncler, Laure Verlin, Meriem Garfa‐Traoré, Nicolas Bourgon, Dhruvin Akbari, Jeanne Porée, Valentina Serpieri, Marine Panza, Lynda Haddad, Patrick Nitschké, Jacqueline Aziza, Cristina Matt, Enza Maria Valente, Patricia Gargallo, Charlotte Dubucs, Tania Attié‐Bitach, Michel R. Leroux, Sophie Thomas   +19 more
wiley   +1 more source

Data from Targeting Sonic Hedgehog-Associated Medulloblastoma through Inhibition of Aurora and Polo-like Kinases

, 2023
Shirley L. Markant, Lourdes Adriana Esparza, Jesse Sun, Kelly L. Barton, Lisa M. McCoig, Gerald A. Grant, John R. Crawford, Michaël Lévy, Paul A. Northcott, David Shih, Marc Remke, Michael D. Taylor, Robert J. Wechsler‐Reya   +12 more
openalex   +1 more source