Results 21 to 30 of about 28,578 (278)

The SOS response regulates adaptive mutation [PDF]

Proceedings of the National Academy of Sciences, 2000
Upon starvation some Escherichia coli cells undergo a transient, genome-wide hypermutation (called adaptive mutation) that is recombination-dependent and appears to be a response to a stressful environment. Adaptive mutation may reflect an inducible mechanism that generates genetic variability in times of stress ...
G J, McKenzie, R S, Harris, P L, Lee, S M, Rosenberg   +3 more
openaire   +2 more sources

The SOS Response of Biofilms [PDF]

International Journal of Clinical & Medical Microbiology, 2016
Background: Biofilms predominate in nearly all nutrient-sufficient ecosystems, both natural and clinical. In clinical settings, bacteria often encounter antimicrobial and DNA damaging agents. Factual evidence shows that more and more biofilm inducing antimicrobials trigger the SOS response of bacteria.
Katie Leiker, Tao Weitao
openaire   +1 more source

Growth‐dependent heterogeneity in the DNA damage response in Escherichia coli

Molecular Systems Biology, 2022
In natural environments, bacteria are frequently exposed to sub‐lethal levels of DNA damage, which leads to the induction of a stress response (the SOS response in Escherichia coli).
Sebastián Jaramillo‐Riveri, James Broughton, Alexander McVey, Teuta Pilizota, Matthew Scott, Meriem El Karoui   +5 more
doaj   +1 more source

A Decrease in the Daily Maximum Temperature during Global Warming Hiatus Causes a Delay in Spring Phenology in the China–DPRK–Russia Cross-Border Area

Remote Sensing, 2022
Spring phenology is the most sensitive indicator of climate change and exploring its response to climate change has important implications for ecosystem processes in the study area.
Minshu Su, Xiao Huang, Zhen Xu, Weihong Zhu, Zhehao Lin   +4 more
doaj   +1 more source

Spring Phenological Sensitivity to Climate Change in the Northern Hemisphere: Comprehensive Evaluation and Driving Force Analysis

Remote Sensing, 2021
Plant phenology depends largely on temperature, but temperature alone cannot explain the Northern Hemisphere shifts in the start of the growing season (SOS).
Kaiwei Li, Chunyi Wang, Qing Sun, Guangzhi Rong, Zhijun Tong, Xingpeng Liu, Jiquan Zhang   +6 more
doaj   +1 more source

Precise temporal modulation in the response of the SOS DNA repair network in individual bacteria. [PDF]

PLoS Biology, 2005
The SOS genetic network is responsible for the repair/bypass of DNA damage in bacterial cells. While the initial stages of the response have been well characterized, less is known about the dynamics of the response after induction and its shutoff.
Nir Friedman, Shuki Vardi, Michal Ronen, Uri Alon, Joel Stavans   +4 more
doaj   +2 more sources

Role of Extracellular DNA in Bacterial Response to SOS-Inducing Drugs

Antibiotics, 2023
The SOS response is a conserved stress response pathway that is triggered by DNA damage in the bacterial cell. Activation of this pathway can, in turn, cause the rapid appearance of new mutations, sometimes called hypermutation.
John K. Crane, Marissa N. Catanzaro
doaj   +1 more source

Lipocalin‐2 activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed Ob/Ob mice

Hepatology, EarlyView., 2022
Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim, Jaewoong Lee, Hyun Joo Shin, Eun Ae Jeong, Hye Min Jang, Yu Jeong Ahn, Hyeong Seok An, Jong Youl Lee, Meong Cheol Shin, Soo Kyoung Kim, Won Gi Yoo, Won Ho Kim, Gu Seob Roh   +12 more
wiley   +1 more source

Quinolone Antibiotics: Resistance and Therapy

Infection and Drug Resistance, 2023
Kai Tang, Heng Zhao Fujian Provincial Key Laboratory of Innate Immune Biology, Fujian Normal University, Fujian, People’s Republic of ChinaCorrespondence: Heng Zhao, Fujian Provincial Key Laboratory of Innate Immune Biology, Fujian Normal University ...
Tang K, Zhao H
doaj  

Analysis of the SOS response of Vibrio and other bacteria with multiple chromosomes

BMC Genomics, 2012
Background The SOS response is a well-known regulatory network present in most bacteria and aimed at addressing DNA damage. It has also been linked extensively to stress-induced mutagenesis, virulence and the emergence and dissemination of antibiotic ...
Sanchez-Alberola Neus, Campoy Susana, Barbé Jordi, Erill Ivan   +3 more
doaj   +1 more source