Results 71 to 80 of about 23,758 (203)
Strongly Monotone Drawings of Planar Graphs [PDF]
, 2016 A straight-line drawing of a graph is a monotone drawing if for each pair of vertices there is a path which is monotonically increasing in some direction, and it is called a strongly monotone drawing if the direction of monotonicity is given by the ...
Felsner, Stefan +5 more
core +2 more sources
Anatomical similarity between the Sost‐knockout mouse and sclerosteosis in humans [PDF]
The Anatomical Record, 2019 AbstractSclerosteosis, a rare autosomal recessive genetic disorder caused by a mutation of the Sost gene, manifests in the facial skeleton by gigantism, facial distortion, mandibular prognathism, cranial nerve palsy, and, in extreme cases, compression of the medulla oblongata.
Uwe Y. Schwarze +3 more
openaire +2 more sources
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.ABSTRACT Background Myofibrillar myopathies (MFM) form a large group of clinically and genetically heterogeneous protein aggregate diseases. We investigated whether a novel quantitative MRI protocol can reveal new aspects of structural and biochemical muscle pathology in three classic MFM subtypes.
Claudius S. Mathy +15 more
wiley +1 more source
Scientific ReportsWnt signaling is critically involved in fracture healing. Existing data predominantly relies on rodent models. Here, we explored local and circulating Dickkopf-1 (DKK1) levels in patients with respect to fracture healing and explore its association to ...
Julia Starlinger +3 more
doaj +1 more source
Frontiers in Oncology, 2022 Retinoblastoma (RB) is the most common intraocular malignancy in children. It has been previously reported that p38 MAPK is related to the pathogenesis of RB. Here we aim at investigating how p38 MAPK affected RB progression through mediating USP22/SIRT1/
Xiaoming Huang +10 more
doaj +1 more source
Journal of Orthopaedic Research, Volume 44, Issue 3, March 2026.ABSTRACT Osteocytes detect and transduce mechanical cues into biochemical signals that regulate bone remodeling. Connexin 43 (Cx43) is the predominant gap junction protein in osteocytes, but its role in β‐catenin signaling during mechanical loading remains unclear.
Michael A. Friedman +5 more
wiley +1 more source
Small Structures, Volume 7, Issue 3, March 2026.This review summarizes advances in bone organoid research over the last 5 years, addressing their definition, distinctive characteristics, construction methods, and applications. It highlights pivotal technologies, contrasts organoid‐based platforms with conventional regeneration methodologies, and explores emerging directions. By recapitulating native
Le Xiao +12 more
wiley +1 more source
Plasma Sclerostin Levels in Rheumatoid Arthritis Women on TNF-α Inhibitor Therapy
PharmaceuticalsRheumatoid arthritis (RA) is associated with significant systemic and local bone loss. The aim of this study was to assess whether or not 15-month tumor necrosis factor α inhibitor (TNFαI) therapy in combination with methotrexate (MTX) affects ...
Anna Szeremeta +4 more
doaj +1 more source
Digital Chinese Medicine, 2019 Objective: To observe the effects of Zhuang Gu Zhi Tong Formula (ZGZTF) on antagonist SOST in canonical Wnt/β-catenin signaling pathway in osteoporosis.
Liu Xiang-Lin +7 more
doaj +1 more source
Direct cell-to-cell interactions between osteocytes and multiple myeloma (MM) cells up-regulate Sost and down-regulate OPG expression in osteocytes: evidence for osteocytic contributions to MM-induced bone disease [PDF]
, 2014 poster abstractOsteocytes are the most abundant bone cells, comprising more than 95% of the cells in bone. They are embedded into the bone matrix, but extensively communicate among themselves and with cells on the bone surface and the bone marrow through
Bellido, T +2 more
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