The transcription factors Egr2 and Egr3 are essential for the control of inflammation and antigen-induced proliferation of B and T cells [PDF]
, 2012 This article is available open access under a Creative Commons license (http://creativecommons.org/licenses/by-nc-nd/3.0/). Copyright @ 2012 Elsevier Inc.Lymphocytes provide optimal responses against pathogens with minimal inflammatory pathology. However,
Miao, T +15 more
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CONSERVED FUNCTIONAL DOMAINS OF THE RNA-POLYMERASE-III GENERAL TRANSCRIPTION FACTOR BRF [PDF]
, 1994 In Saccharomyces cerevisiae, two components of the RNA polymerase III (Pol III) general transcription factor TFIIIB are the TATA-binding protein (TBP) and the B-related factor (BRF), so called because its amino-terminal half is homologous to the Pol II ...
JACKSON, SP, BROPHY, B, KHOO, B
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Metabolic control through the PGC-1 family of transcription coactivators [PDF]
, 2005 Many complex biological programs are controlled at the level of gene transcription by DNA binding transcription factors. Recent studies have revealed a novel mode of regulation by coactivator proteins, best illustrated by the PGC-1 family of coactivators.
Lin, J. +8 more
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Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivo [PDF]
, 2006 The transcription factors lymphoid enhancer binding factor 1 (LEF1) and transcription factor 7 (TCF7) (T cell factor-1 (TCF-1)) are downstream effectors of the WNT signaling pathway, which is a critical regulator of T cell development in the thymus.
Freeman, Tom +5 more
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Chapter 5 Synthesis and Evaluation of Polyamide-Isoxazolidine
, 2014 Pyrrole-Imidazole hairpin polyamides are a cell-permeable class of DNA-binding small molecules that are able to access chromatin and disrupt the transcription factor-DNA binding interface, thereby downregulating endogenous gene expression in human ...
Conjugates Artificial +1 more
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MYB transcription factors that colour our fruit
, 2008 Anthocyanin concentration is a primary determinant of plant colour. Fruit anthocyanin biosynthesis is controlled by a distinct clade of R2R3 MYB transcription factors.
Hellens, R.P., Allan, A.C., Laing, W.A.
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Understanding how adult stem cells generate neurons is critical for advancing regenerative medicine, yet few in vivo models allow for the direct study of adult stem cell fate specification. The planarian Schmidtea mediterranea offers a powerful system to
Cathell, Mallory
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Analyses of the archaeal transcription cycle reveal a mosaic of eukaryotic RNA polymerase II and III-like features [PDF]
, 2009 Novel mechanistic properties of the archaeal transcription system that reveal similarities especially to the eukaryotic RNA polymerase II and III systems were presented in thesis.
Spitalny, Patrizia
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MOLECULAR MECHANISMS OF DRUG RESISTANCE IN CANDIDA ALBICANS: ROLE OF TRANSCRIPTION FACTORS MCM1 AND ADA2 [PDF]
, 2011 Candida albicans is an opportunistic fungal pathogen responsible for localized as well as disseminated infections. C. albicans is the most commonly isolated specie from blood cultures, accounting for over 60% of all Candida isolates. The fungistatic drug
MOGAVERO, SELENE
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Walking, hopping and jumping: a model of transcription factor dynamics on DNA [PDF]
, 2011 We present a model of how transcription factors scan DNA to find their specific binding sites. Following the classical work of Winter et al. (1981), our model assumes two modes of transcription factor dynamics.
Barnes, David J., Chu, Dominique
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