Results 41 to 50 of about 7,860,410 (130)

SOX2 and cancer: current research and its implications in the clinic

Clinical and Translational Medicine, Volume 3, Issue 1, December 2014., 2014
Abstract SOX2 is a gene that encodes for a transcription factor belonging to the SOX gene family and contains a high‐mobility group (HMG) domain, which permits highly specific DNA binding. Consequently, SOX2 functions as an activator or suppressor of gene transcription.
Kasia Weina, Jochen Utikal
wiley   +1 more source

An RxLR effector from phytophthora infestans prevents re-localisation of two plant NAC transcription factors from the endoplasmic reticulum to the nucleus [PDF]

, 2013
The plant immune system is activated following the perception of exposed, essential and invariant microbial molecules that are recognised as non-self. A major component of plant immunity is the transcriptional induction of genes involved in a wide array ...
McLellan, Hazel, Petra C Boevink, Beynon Jim L., Gomez, Sonia, Beynon, Jim L., Jim L. Beynon (469129), Boevink Petra C., Beynon, Jim, Whisson, Stephen C., Birch, Paul R. J.; id_orcid, Boevink, Petra, Petra C. Boevink (394247), Pritchard Leighton, Armstrong Miles R., Hazel McLellan, Miles R. Armstrong (469126), Gomez Sonia, Pritchard, Leighton, Juan Morales, Jim L Beynon, Hazel McLellan (469125), Armstrong, Miles, Birch, Paul R. J., Sonia Gomez (469127), Birch Paul R. J., Morales, Juan, Leighton Pritchard, Paul R J Birch, Sonia Gomez, Leighton Pritchard (173498), Stephen C Whisson, McLellan Hazel, Armstrong, Miles R., Paul R. J. Birch (132138), Stephen C. Whisson (110493), Boevink, Petra C., Gómez-Galera, Sonia, Miles R Armstrong, Whisson Stephen C., Morales Juan, Whisson, steve, Juan Morales (469128)   +41 more
core   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy, Dávid Mező, Kinga K. Nagy, Viktória Perey‐Simon, Judit Tóth, Angéla Békési, Beáta Vértessy, Máté Varga   +7 more
wiley   +1 more source

The Spectrum of Anti‐Chromatin/Nucleosome Autoantibodies: Independent and Interdependent Biomarkers of Disease

Journal of Immunology Research, Volume 2014, Issue 1, 2014., 2014
Autoantibodies directed to chromatin components date back to the discovery of the LE cell and the LE cell phenomenon circa 1950, and subsequent evidence that major components of that reaction were chromatin components and histones in particular.
Sonal Mehra, Marvin J. Fritzler, Michael Mahler   +2 more
wiley   +1 more source

Cheminformatics analysis of molecular datasets of transcription factors associated with quorum sensing in Pseudomonas aeruginosa [PDF]

, 2021
Transcription factors associated with quorum sensing in P. aeruginosa are promising targets for developing new adjuvants against infection by this pathogen.
Norberto, Sánchez-Cruz, Fabian , López-Vallejo, José L., Medina-Franco, Felipe, Victoria-Muñoz   +3 more
core   +1 more source

Genetic Mechanism That Defines the Characteristic Neurogenesis Patterns in the Neural Plate Using Hes/her Genes During Early Vertebrate Development

genesis, Volume 63, Issue 3, June 2025.
ABSTRACT In the early zebrafish neural plate, proneural cluster domains are defined by surrounding neural progenitor pools (NPPs), generating primary neurogenesis patterns. In each NPP, several Notch‐independent Hes/her‐type genes are expressed in distinct manners.
Takero Ohyanagi, Hiroki Tokizaki, Takehisa Sato, Momo Tsuruoka, Kyo Yamasu   +4 more
wiley   +1 more source

Identification and expression analysis of Sox family genes in echinoderms

BMC Genomics
The Sox gene family, a collection of transcription factors widely distributed throughout the animal kingdom, plays a crucial role in numerous developmental processes.
Xiaojing Li, Tiangui Cao, Hui Liu, Longhai Fu, Quanchao Wang   +4 more
doaj   +1 more source

Cellular‐resolution gene expression mapping reveals organization in the head ganglia of the gastropod, Berghia stephanieae

Journal of Comparative Neurology, Volume 532, Issue 6, June 2024.
Graphical Abstract: We used single‐cell transcriptomics to explore cell type and neuronal class diversity, and in situ hybridization chain reaction to view expression in the brain of the nudibranch mollusc, Berghia stephanieae. Gene markers for nudibranch neurons and glia were found.
M. Desmond Ramirez, Thi N. Bui, Paul S. Katz   +2 more
wiley   +1 more source

Structures of the Ets Protein DNA-binding Domains of Transcription Factors Etv1, Etv4, Etv5, and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation. [PDF]

, 2015
Ets transcription factors, which share the conserved Ets DNA-binding domain, number nearly 30 members in humans and are particularly involved in developmental processes.
Allerston, Charles K., Gileadi, Opher, Cooper, Christopher D.O., Newman, Joseph A., Aitkenhead, Hazel   +4 more
core   +1 more source

Elongation of the developing spinal cord is driven by Oct4‐type transcription factor‐mediated regulation of retinoic acid signaling in zebrafish embryos

Developmental Dynamics, Volume 253, Issue 4, Page 404-422, April 2024.
Abstract Background Elongation of the spinal cord is dependent on neural development from neuromesodermal progenitors in the tail bud. We previously showed the involvement of the Oct4‐type gene, pou5f3, in this process in zebrafish mainly by dominant‐interference gene induction, but, to compensate for the limitation of this transgene approach, mutant ...
Tatsuya Yuikawa, Takehisa Sato, Masaaki Ikeda, Momo Tsuruoka, Kaede Yasuda, Yuto Sato, Kouhei Nasu, Kyo Yamasu   +7 more
wiley   +1 more source