Results 31 to 40 of about 2,990 (93)

Regeneration of Zebrafish CNS: Adult Neurogenesis

Neural Plasticity, Volume 2016, Issue 1, 2016., 2016
Regeneration in the animal kingdom is one of the most fascinating problems that have allowed scientists to address many issues of fundamental importance in basic biology. However, we came to know that the regenerative capability may vary across different species.
Sukla Ghosh, Subhra Prakash Hui, Juan Nacher   +2 more
wiley   +1 more source

SOX2 and cancer: current research and its implications in the clinic

Clinical and Translational Medicine, Volume 3, Issue 1, December 2014., 2014
Abstract SOX2 is a gene that encodes for a transcription factor belonging to the SOX gene family and contains a high‐mobility group (HMG) domain, which permits highly specific DNA binding. Consequently, SOX2 functions as an activator or suppressor of gene transcription.
Kasia Weina, Jochen Utikal
wiley   +1 more source

The Spectrum of Anti‐Chromatin/Nucleosome Autoantibodies: Independent and Interdependent Biomarkers of Disease

Journal of Immunology Research, Volume 2014, Issue 1, 2014., 2014
Autoantibodies directed to chromatin components date back to the discovery of the LE cell and the LE cell phenomenon circa 1950, and subsequent evidence that major components of that reaction were chromatin components and histones in particular.
Sonal Mehra, Marvin J. Fritzler, Michael Mahler   +2 more
wiley   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy, Dávid Mező, Kinga K. Nagy, Viktória Perey‐Simon, Judit Tóth, Angéla Békési, Beáta Vértessy, Máté Varga   +7 more
wiley   +1 more source

Genetic Mechanism That Defines the Characteristic Neurogenesis Patterns in the Neural Plate Using Hes/her Genes During Early Vertebrate Development

genesis, Volume 63, Issue 3, June 2025.
ABSTRACT In the early zebrafish neural plate, proneural cluster domains are defined by surrounding neural progenitor pools (NPPs), generating primary neurogenesis patterns. In each NPP, several Notch‐independent Hes/her‐type genes are expressed in distinct manners.
Takero Ohyanagi, Hiroki Tokizaki, Takehisa Sato, Momo Tsuruoka, Kyo Yamasu   +4 more
wiley   +1 more source

Cellular‐resolution gene expression mapping reveals organization in the head ganglia of the gastropod, Berghia stephanieae

Journal of Comparative Neurology, Volume 532, Issue 6, June 2024.
Graphical Abstract: We used single‐cell transcriptomics to explore cell type and neuronal class diversity, and in situ hybridization chain reaction to view expression in the brain of the nudibranch mollusc, Berghia stephanieae. Gene markers for nudibranch neurons and glia were found.
M. Desmond Ramirez, Thi N. Bui, Paul S. Katz   +2 more
wiley   +1 more source

Elongation of the developing spinal cord is driven by Oct4‐type transcription factor‐mediated regulation of retinoic acid signaling in zebrafish embryos

Developmental Dynamics, Volume 253, Issue 4, Page 404-422, April 2024.
Abstract Background Elongation of the spinal cord is dependent on neural development from neuromesodermal progenitors in the tail bud. We previously showed the involvement of the Oct4‐type gene, pou5f3, in this process in zebrafish mainly by dominant‐interference gene induction, but, to compensate for the limitation of this transgene approach, mutant ...
Tatsuya Yuikawa, Takehisa Sato, Masaaki Ikeda, Momo Tsuruoka, Kaede Yasuda, Yuto Sato, Kouhei Nasu, Kyo Yamasu   +7 more
wiley   +1 more source

Early nervous system development in the chaetognath Spadella cephaloptera exhibits conserved bilaterian patterning features

Frontiers in Cell and Developmental Biology
Nervous systems display extensive diversity in structure and organization, yet a broadly conserved set of signaling pathway components and transcription factors is consistently associated with early neurogenesis in many animal lineages.
June F. Ordoñez, June F. Ordoñez, Alice Frisinghelli, Alice Frisinghelli, Cristian Camilo Barrera Grijalba, Cristian Camilo Barrera Grijalba, Tim Wollesen   +6 more
doaj   +1 more source

Editorial: The development and evolution of larval nervous systems. [PDF]

Front Neurosci
Vöcking O, Carrillo-Baltodano A, Meyer NP.   +2 more
europepmc   +1 more source

Aberrant DNA methylation of SOX1 and PAX1 as epigenetic biomarkers and prognostic indicators in oral squamous cell carcinoma: a single-centre retrospective study. [PDF]

BMC Oral Health
Lin Y, Li X, Shao L, Ma Z, Liu A, Li Z.
europepmc   +1 more source