A local regulatory network around three NAC transcription factors in stress responses and senescence in Arabidopsis leaves [PDF]
A model is presented describing the gene regulatory network surrounding three similar NAC transcription factors that have roles in Arabidopsis leaf senescence and stress responses. ANAC019, ANAC055 and ANAC072 belong to the same clade of NAC domain genes
Cooke, Emma J. +31 more
core +1 more source
Distinct SoxB1 networks are required for naïve and primed pluripotency [PDF]
Deletion ofSox2from embryonic stem cells (ESCs) causes trophectodermal differentiation. While this can be prevented by enforced expression of the related SOXB1 proteins, SOX1 or SOX3, the roles of SOXB1 proteins in epiblast stem cell (EpiSC) pluripotency
Elham S. Mirfazeli +13 more
core +2 more sources
Adult Neural Stem Cells: Basic Research and Production Strategies for Neurorestorative Therapy
Over many decades, constructing genetically and phenotypically stable lines of neural stem cells (NSC) for clinical purposes with the aim of restoring irreversibly lost functions of nervous tissue has been one of the major goals for multiple research groups. The unique ability of stem cells to maintain their own pluripotent state even in the adult body
E. M. Samoilova +6 more
wiley +1 more source
CoryneRegNet: An ontology-based data warehouse of corynebacterial transcription factors and regulatory networks [PDF]
Baumbach J, Brinkrolf K, Czaja LF, Rahmann S, Tauch A. CoryneRegNet: An ontology-based data warehouse of corynebacterial transcription factors and regulatory networks. BMC Genomics.
Baumbach Jan +9 more
core +1 more source
Inner ear formation requires that a series of cell fate decisions and morphogenetic events occur in a precise temporal and spatial pattern. Previous studies have shown that transcription factors, including Pax2, Sox2, and Prox1, play important roles during the inner ear development.
Shaofeng Liu +11 more
wiley +1 more source
Turnover and function of DNA methylation at transcription factor binding sites [PDF]
Cell type identity is largely determined by regulatory networks consistent of various transcription factors. Transcription factor activity requires interaction with DNA and thus critically depends on the accessibility of binding motifs.
Feldmann, Angelika
core +1 more source
Reverse genetics and next‐generation sequencing unlocked a new era in biology. It is now possible to identify an animal(s) with the unique biology most relevant to a particular question and rapidly generate tools to functionally dissect that biology. This review highlights the rise of one such novel model system, the starlet sea anemone Nematostella ...
Michael J. Layden +2 more
wiley +1 more source
An R2R3 MYB transcription factor associated with regulation of the anthocyanin biosynthetic pathway in Rosaceae [PDF]
Background The control of plant anthocyanin accumulation is via transcriptional regulation of the genes encoding the biosynthetic enzymes. A key activator appears to be an R2R3 MYB transcription factor.
Wang, Kui-Lin +32 more
core +2 more sources
Regeneration of Zebrafish CNS: Adult Neurogenesis
Regeneration in the animal kingdom is one of the most fascinating problems that have allowed scientists to address many issues of fundamental importance in basic biology. However, we came to know that the regenerative capability may vary across different species.
Sukla Ghosh +2 more
wiley +1 more source
Identification and validation of transcription factors that regulate chromatin dynamics [PDF]
Gene expression has to be tightly regulated during all cellular processes. During embryonic development differentiating cells loose their developmental potential and acquire specific functions by activating lineage-specific genes.
Schöler, Anne
core +1 more source

