Results 31 to 40 of about 7,860,410 (130)

A local regulatory network around three NAC transcription factors in stress responses and senescence in Arabidopsis leaves [PDF]

open access: yes, 2013
A model is presented describing the gene regulatory network surrounding three similar NAC transcription factors that have roles in Arabidopsis leaf senescence and stress responses. ANAC019, ANAC055 and ANAC072 belong to the same clade of NAC domain genes
Cooke, Emma J.   +31 more
core   +1 more source

Distinct SoxB1 networks are required for naïve and primed pluripotency [PDF]

open access: yes, 2017
Deletion ofSox2from embryonic stem cells (ESCs) causes trophectodermal differentiation. While this can be prevented by enforced expression of the related SOXB1 proteins, SOX1 or SOX3, the roles of SOXB1 proteins in epiblast stem cell (EpiSC) pluripotency
Elham S. Mirfazeli   +13 more
core   +2 more sources

Adult Neural Stem Cells: Basic Research and Production Strategies for Neurorestorative Therapy

open access: yesStem Cells International, Volume 2018, Issue 1, 2018., 2018
Over many decades, constructing genetically and phenotypically stable lines of neural stem cells (NSC) for clinical purposes with the aim of restoring irreversibly lost functions of nervous tissue has been one of the major goals for multiple research groups. The unique ability of stem cells to maintain their own pluripotent state even in the adult body
E. M. Samoilova   +6 more
wiley   +1 more source

CoryneRegNet: An ontology-based data warehouse of corynebacterial transcription factors and regulatory networks [PDF]

open access: yes, 2006
Baumbach J, Brinkrolf K, Czaja LF, Rahmann S, Tauch A. CoryneRegNet: An ontology-based data warehouse of corynebacterial transcription factors and regulatory networks. BMC Genomics.
Baumbach Jan   +9 more
core   +1 more source

The Key Transcription Factor Expression in the Developing Vestibular and Auditory Sensory Organs: A Comprehensive Comparison of Spatial and Temporal Patterns

open access: yesNeural Plasticity, Volume 2018, Issue 1, 2018., 2018
Inner ear formation requires that a series of cell fate decisions and morphogenetic events occur in a precise temporal and spatial pattern. Previous studies have shown that transcription factors, including Pax2, Sox2, and Prox1, play important roles during the inner ear development.
Shaofeng Liu   +11 more
wiley   +1 more source

Turnover and function of DNA methylation at transcription factor binding sites [PDF]

open access: yes, 2014
Cell type identity is largely determined by regulatory networks consistent of various transcription factors. Transcription factor activity requires interaction with DNA and thus critically depends on the accessibility of binding motifs.
Feldmann, Angelika
core   +1 more source

The rise of the starlet sea anemone Nematostella vectensis as a model system to investigate development and regeneration

open access: yesWIREs Developmental Biology, Volume 5, Issue 4, Page 408-428, July/August 2016., 2016
Reverse genetics and next‐generation sequencing unlocked a new era in biology. It is now possible to identify an animal(s) with the unique biology most relevant to a particular question and rapidly generate tools to functionally dissect that biology. This review highlights the rise of one such novel model system, the starlet sea anemone Nematostella ...
Michael J. Layden   +2 more
wiley   +1 more source

An R2R3 MYB transcription factor associated with regulation of the anthocyanin biosynthetic pathway in Rosaceae [PDF]

open access: yes, 2010
Background The control of plant anthocyanin accumulation is via transcriptional regulation of the genes encoding the biosynthetic enzymes. A key activator appears to be an R2R3 MYB transcription factor.
Wang, Kui-Lin   +32 more
core   +2 more sources

Regeneration of Zebrafish CNS: Adult Neurogenesis

open access: yesNeural Plasticity, Volume 2016, Issue 1, 2016., 2016
Regeneration in the animal kingdom is one of the most fascinating problems that have allowed scientists to address many issues of fundamental importance in basic biology. However, we came to know that the regenerative capability may vary across different species.
Sukla Ghosh   +2 more
wiley   +1 more source

Identification and validation of transcription factors that regulate chromatin dynamics [PDF]

open access: yes, 2012
Gene expression has to be tightly regulated during all cellular processes. During embryonic development differentiating cells loose their developmental potential and acquire specific functions by activating lineage-specific genes.
Schöler, Anne
core   +1 more source

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