Results 11 to 20 of about 2,990 (93)
Transcriptome Analysis Suggested Striking Transition Around the End of Epiboly in the Gene Regulatory Network Downstream of the Oct4-Type POU Gene in Zebrafish Embryos. [PDF]
Dev Growth DifferTranscriptome analysis of pou5f3‐regulated genes in zebrafish embryos showed that competence to pou5f3 regulation changes significantly before and after the end of epiboly. The target genes encoded a diverse array of proteins, including transcriptional regulators and signaling molecules.
Ikeda M +6 more
europepmc +2 more sources
Dbx1 is a direct target of SOX3 in the spinal cord. [PDF]
PLoS ONE, 2014 SoxB1 sub-family of transcriptional regulators are expressed in progenitor (NP) cells throughout the neuroaxis and are generally downregulated during neuronal differentiation.
Nicholas Rogers +2 more
doaj +1 more source
Identification and expression analysis of Sox family genes in echinoderms. [PDF]
BMC GenomicsThe Sox gene family, a collection of transcription factors widely distributed throughout the animal kingdom, plays a crucial role in numerous developmental processes.
Li X, Cao T, Liu H, Fu L, Wang Q.
europepmc +2 more sources
Frontiers in Cell and Developmental Biology, 2022 In vertebrates, the four transcription factors Sox2, c-Myc, Pou5f1 and Klf4 are involved in the differentiation of several tissues during vertebrate embryogenesis; moreover, they are normally co-expressed in embryonic stem cells and play roles in ...
Virginia Vanni +9 more
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Analyses of Sox-B and Sox-E Family Genes in the Cephalopod Sepia officinalis: Revealing the Conserved and the Unusual. [PDF]
PLoS ONE, 2016 Cephalopods provide an unprecedented opportunity for comparative studies of the developmental genetics of organ systems that are convergent with analogous vertebrate structures. The Sox-family of transcription factors is an important class of DNA-binding
Laura Focareta, Alison G Cole
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An insight into planarian regeneration
Cell Proliferation, Volume 55, Issue 9, September 2022., 2022 Genetic and molecular mechanisms for regeneration control on various tissues in planarian. Abstract Background Planarian has attracted increasing attentions in the regeneration field for its usefulness as an important biological model organism attributing to its strong regeneration ability.
Xin‐Yang Ge +4 more
wiley +1 more source
Involvement of ubiquitous and tale transcription factors, as well as liganded RXRα, in the regulation of human SOX2 gene expression in the NT2/D1 embryonal carcinoma cell line [PDF]
Archives of Biological Sciences, 2010 SOX2 is a key transcription factor in embryonic development representing a universal marker of pluripotent stem cells. Based on the functional redundancy and overlapping expression patterns of SOXB1 subgroup members during development, the goal of this ...
Milivojević Milena +6 more
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Reviews in Aquaculture, Volume 13, Issue 4, Page 1986-2003, September 2021., 2021 Abstract The Sry‐related high mobility group box (Sox) genes family is a group of transcription factors playing crucial roles during reproduction and development. At least 50% amino acid sequences of Sox protein family are similarity to the sex‐determining region on the Y chromosome (Sry).
Yacheng Hu, Binzhong Wang, Hejun Du
wiley +1 more source
BioEssays, Volume 43, Issue 7, July 2021., 2021 Development and maintenance of organs requires context‐specific regulation of stem cell activities. We hypothesize that these are dependent upon reciprocal interactions between the cell‐cycle machinery and regulators of stem cell differentiation. To support this, we discuss the mechanistic links between these processes, as well as their parallel ...
Jonas Muhr, Daniel W. Hagey
wiley +1 more source
In Silico Identification of SOX1 Post-Translational Modifications Highlights a Shared Protein Motif
Cells, 2020 The transcription factor SOX1 is a key regulator of neural stem cell development, acting to keep neural stem cells (NSCs) in an undifferentiated state. Postnatal expression of Sox1 is typically confined to the central nervous system (CNS), however, its ...
Azaz Ahmad +4 more
doaj +1 more source