Results 61 to 70 of about 3,357 (240)

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

Advanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu, Hongyuan Zhang, Tayyiba Azam, Susanne S. Hille, Yingjuan Liu, Min Zi, Jiaqing Lang, He Yu, Yujia Cao, Bernard D. Keavney, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Ming Xu, Elizabeth J. Cartwright, Oliver J. Müller, Ming Lei, Xin Wang   +17 more
wiley   +1 more source

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

Advanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan, Lixin Tian, Lianjie Peng, Jingyu Zhang, Lining Lin, Xiaoting Zhang, Yaxian Luo, Zhichao Liu, Xinhua Yao, Mouyuan Sun, Yong He, Mengfei Yu, Huiming Wang   +12 more
wiley   +1 more source

Improved Direct Ink Writing of Liquid Metal Foams via Liquid Additives

Advanced Electronic Materials, EarlyView.
The ability to pattern liquid metal is useful for making soft electrical and thermal devices. Dispensing liquid metal from a nozzle naturally results in the formation of spheroidal droplets, making direct‐write printing challenging. Liquid metal foams containing pockets of air can extrude as filaments, albeit inconsistently.
Febby Krisnadi, Tushar Sakorikar, Man Hou Vong, Michael D. Dickey   +3 more
wiley   +1 more source

Assessment of In Vitro Nano‐Cytotoxicity Through Fluorescence Microscopy via Neural Network‐Based Live/Dead Cell Classification

Advanced Intelligent Systems, EarlyView.
FluoAI is a two‐stage, label‐free method for quantifying nanomaterial‐induced cytotoxicity from conventional fluorescence microscopy images. Mask R‐CNN segmentation and DenseNet‐121 classification provide rapid live/dead classification matching human accuracy.
Ugur C. Topkiran, Ali Gasimli, Lal Durmaz, Diya Vashani, Himish Paul, Giridhar R. Akkaraju, Anton V. Naumov   +6 more
wiley   +1 more source

Strategi Pemanfaatan Perairan Pesisir untuk Budi Daya Kerang Hijau (Perna viridis L.) di Kuala Langsa, Provinsi Aceh

Jurnal Ilmu Pertanian Indonesia, 2017
Development of green mussel culture currently still requires the determination of strategies in accordance with the potential and conditions of coastal areas as well as management culture system.
Andi Sagita, Rahmat Kurnia, Sulistiono
doaj   +1 more source

Integrating machine learning, deep learning, and image analysis for seed species classification

Applications in Plant Sciences, EarlyView.
Abstract Premise The growing demand for wildflower seeds in ecological restoration requires reliable species identification, yet current market products often contain heterogeneous species. As seed identification is labor‐intensive and requires advanced botanical knowledge, we evaluated multiple segmentation and classification approaches to determine ...
Jonathan Ashworth, Eloise Barrett, Rebonto Haque, Ben Wildey, Anthony Hall, Felix Shaw, Jose J. De Vega   +6 more
wiley   +1 more source

A detailed redescription of a skeletally immature ‘Redondasaurus’ suggests ontogenetic transformations in the taxon mirror phytosaurian morphological evolution

The Anatomical Record, EarlyView.
Abstract The study of morphological evolution is fundamentally tied to ontogeny, yet studies of these heterochronic processes in the fossil record are rare. Fossils belonging to an ontogenetic series are difficult to assign to an ontogenetic stage due to inconsistent proxies for skeletal ages, challenging to taxonomically assign due to morphological ...
Erika R. Goldsmith, Michelle R. Stocker
wiley   +1 more source

Influences of different collector materials on Mediterranean Mussel, Mytilus galloprovincialis L. 1819 in the Dardanelles.

Marine Science and Technology Bulletin, 2013
The present study is carried out in Kilya Bay (in the Dardanelles) between February 2002 and February 2004. The purpose of this study was to determine the most suitable collector material, time to collect mussel seed, and the growth rate.
Harun Yıldız, Aynur Lök, Sefa Acarlı, Serpil Serdar, Aysun Küçükdermenci, Selçuk Berber, Pervin Vural   +6 more
doaj  

The skeleton of the green Iguana iguana (Squamata: Iguanidae) and its intraspecific morphological variation

The Anatomical Record, EarlyView.
Abstract The green iguana (Iguana iguana) is an iguanine lizard with herbivorous and arboreal habits, whose distribution spans through South America, Central America to the south of North America. Although the genus Iguana is well‐known, the species still lacks a comprehensive and up‐to‐date anatomical study, particularly addressing the axial skeleton,
Vieno Rosa, Marcos Vinícius Coelho, Camila Cupello   +2 more
wiley   +1 more source

Oldest well‐preserved euprimate petrosal, from the early Eocene of India (Vastan Lignite Mine, Gujarat)

The Anatomical Record, EarlyView.
Abstract An exquisitely preserved, isolated partial petrosal with associated fragmentary stapes is described from the Vastan Lignite Mine (Gujarat, India), dated to the early Eocene (~54.5 Ma). Several anatomical traits (e.g., large petrosal plate; posterolateral entry of the internal carotid artery to the tympanic cavity; bony tubes surrounding the ...
Mary T. Silcox, Kenneth D. Rose, Rachel H. Dunn, Kishor Kumar, Rajendra S. Rana, Ashok Sahni, Lachham Singh, Thierry Smith, Jordan W. Crowell   +8 more
wiley   +1 more source