Results 111 to 120 of about 158,858 (186)

Plasma exchange and radiation resensitize immunotherapy-refractory melanoma: a phase I trial

Nature Communications
Immune checkpoint inhibitors (ICI) are effective for advanced melanoma. However, most develop ICI resistance. Tumor-derived soluble PD-L1 (sPD-L1) and other immunosuppressive factors drive resistance. We hypothesized that therapeutic plasma exchange (TPE)
Jacob J. Orme, Henan Zhang, Prashanth Lingamaneni, Yohan Kim, Roxane Lavoie, Maddy Dorr, Paul Dizona, Jacob Hirdler, Elizabeth A. Bering, Joanina K. Gicobi, Michelle Hsu, Heather Dale, Daniel S. Childs, Lisa A. Kottschade, Robert R. McWilliams, Matthew S. Block, Aaron S. Mansfield, Svetomir N. Markovic, Ken Olivier, Dawn Owen, Scott Lester, Daniel Ma, Roxana S. Dronca, Haidong Dong, Fabrice Lucien, Annie T. Packard, Jeffrey L. Winters, Sean S. Park   +27 more
doaj   +1 more source

On the dual of a mixed H2/l1 optimisation problem

, 2006
The general discrete-time Single-Input Single-Output (SISO) mixed H2/l1 control problem is considered in this paper. It is found that the existing results of duality theory cannot be directly applied to this infinite dimension optimisation problem.
Chu, J., Wu, J., Chen, S.
core  

Mutations in the extracellular domain of the neural cell adhesion molecule L1 impair protein trafficking in vitro and in vivo

, 2002
Rünker AE. Mutations in the extracellular domain of the neural cell adhesion molecule L1 impair protein trafficking in vitro and in vivo. Bielefeld (Germany): Bielefeld University; 2002.Das neurale Zelladhäsionsmolekül L1 ist ein Mitglied der ...
Rünker, Annette E.
core  

Soluble Programmed Death-Ligand 1 (sPD-L1) as a Promising Marker for Head and Neck Squamous Cell Carcinoma: Correlations With Clinical and Demographic Characteristics. [PDF]

Cureus, 2023
Alrehaili AA, Gharib AF, Almalki A, Alghamdi A, Hawsawi NM, Bakhuraysah MM, Alhuthali HM, Etewa RL, Elsawy WH.   +8 more
europepmc   +1 more source

Retracted: The Change of Soluble Programmed Death Ligand 1 (sPD-L1) in Plasma of Small Cell Lung Cancer and Its Clinical Significance. [PDF]

Comput Math Methods Med, 2023
Methods In Medicine CAM.
europepmc   +1 more source

Genetic Variants and Soluble Isoforms of PD-1/PD-L1 as Novel Biomarkers for Pancreatic Ductal Adenocarcinoma (PDAC) Susceptibility and Prognosis

Biomedicines
Background: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive neoplasm often diagnosed at advanced stages. Immune checkpoint molecules, particularly programmed cell death protein-1 (PD-1) and its ligand PD-L1, are pivotal in tumor immune ...
Marwa Hassan, Walaa H. El-Maadawy, Yasmine Elhusseny, Fatma Elbatol Agamy, Sally A. Fahim, Mahmoud Balata   +5 more
doaj   +1 more source

Correlation of Soluble Programmed Death Ligand-1 (sPD-L1) with Alpha-Fetoprotein Levels as a Predictor of Prognosis in Hepatocellular Carcinoma Patients

Background: Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and one of the leading causes of cancer death worldwide. Chronic hepatitis B virus infection is the most common etiology of HCC. Programmed death ligand-1 (PD-L1) is a
Mgs M. Irsan Saleh, Chaerunisah, Sari, Suyata   +2 more
core   +1 more source

sPD-L1在肺癌患者血清及胸膜腔积液中水平差异及相关性分析

Zhongguo shiyan zhenduanxue, 2020
目的分别检测肺腺癌和肺鳞癌患者血清及胸膜腔积液中sPD-L1水平的差异并进行相关性分析。方法收集2016年12月至2018年5月于重庆三峡中心医院就诊,伴发恶性胸膜腔积液的肺腺癌和肺鳞癌患者的外周血和胸膜腔积液,采用试剂盒检测sPD-L1水平,并对检测结果进行统计学分析。结果 sPD-L1在肺腺癌患者外周血和胸膜腔积液中的表达水平分别为1.71±0.13(ng/mL)和1.26±0.11(ng/mL),在肺鳞癌患者外周血和胸膜腔积液中的表达水平分别为1.86±0.30(ng/mL)和0.89±0.14 ...
赵爽, 熊芳
doaj  

Thymoquinone, a Novel Multi-Strike Inhibitor of Pro-Tumorigenic Breast Cancer (BC) Markers: CALR, NLRP3 Pathway and sPD-L1 in PBMCs of HR+ and TNBC Patients. [PDF]

Int J Mol Sci, 2023
Elgohary S, Eissa RA, El Tayebi HM.
europepmc   +1 more source

An L1 estimation algorithm with degeneracy and linear constraints

, 2002
An implementation of the reduced gradient algorithm is proposed to solve the linear L1 estimation problem (least absolute deviations regression) with linear equality or inequality constraints, including rank deficient and degenerate cases.
Shi, M., Lukas, M.A.
core