Results 271 to 280 of about 72,291,708 (309)
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Achieving resistance specificity in prostate cancer
Chemico-Biological Interactions, 2016Prostate (CaP) cancer is the second-leading cause of cancer-related mortality in men in Western societies. Androgen receptor (AR) signaling is a critical survival pathway for prostate cancer cells, and androgen-deprivation therapy (ADT) remains the principal treatment for patients with locally advanced and metastatic disease.
Bhumika, Wadhwa, Rashmi, Dumbre
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Tissue-specificity of insulin action and resistance*
Archives of Physiology and Biochemistry, 2011Insulin resistance is the most important pathophysiological feature in many pre-diabetic states. Type 2 diabetes mellitus is a complex metabolic disease and its pathogenesis involves abnormalities in both peripheral insulin action and insulin secretion by pancreatic beta cells.
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Biofilm-specific antibiotic tolerance and resistance
European Journal of Clinical Microbiology & Infectious Diseases, 2015Biofilms are heterogeneous structures composed of bacterial cells surrounded by a matrix and attached to solid surfaces. The bacteria here are 100 to 1,000 times more tolerant to antimicrobials than corresponding planktonic cells. Biofilms can be difficult to eradicate when they cause biofilm-related diseases, e.g., implant infections, cystic fibrosis,
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Antibiotic resistance in the patient with cancer: Escalating challenges and paths forward
Ca-A Cancer Journal for Clinicians, 2021Amila Nanayakkara, David E Greenberg
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Molecular mechanisms of antibiotic resistance revisited
Nature Reviews Microbiology, 2022Jessica M A Blair +2 more
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Antibiotic resistance in the environment
Nature Reviews Microbiology, 2021Carl-Fredrik Flach, D G Joakim Larsson
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Tackling the emerging threat of antifungal resistance to human health
Nature Reviews Microbiology, 2022Adilia Warris +2 more
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