Results 71 to 80 of about 32,241 (268)

Building evaluation using two components of acceleration time histories causes by shallow crustal fault earthquakes with maximum magnitude 7 Mw

open access: yesMATEC Web of Conferences, 2018
Spectral acceleration and acceleration time histories are the two seismic loads generally used for dynamic analysis of a building. The structural design of buildings is implemented using spectral acceleration at the ground surface obtained from the ...
Partono Windu   +5 more
doaj   +1 more source

Accelerating spectral clustering on quantum and analog platforms

open access: yesAcademia Quantum
We introduce a novel hybrid quantum–analog algorithm to perform a graph clustering that exploits connections between the evolution of dynamical systems on graphs and the underlying graph spectra. This approach constitutes a new class of algorithms that combine emerging quantum and analog platforms to accelerate computations.
Xu, Xingzi, Sahai, Tuhin
openaire   +2 more sources

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo   +9 more
wiley   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin   +11 more
wiley   +1 more source

Kernel Density Estimation Based Gaussian and Non-Gaussian Random Vibration Data Induction for High-Speed Train Equipment

open access: yesIEEE Access, 2020
Because general statistics tolerance is not applicable to the induction of non-Gaussian vibration data and the methods for converting non-Gaussian data into Gaussian data are not always effective and can increase the estimation error, a novel kernel ...
Peng Wang   +4 more
doaj   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron   +5 more
wiley   +1 more source

Accelerating Spectral Clustering under Fairness Constraints

open access: yes
ICML ...
Tonin, Francesco   +3 more
openaire   +2 more sources

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas   +39 more
wiley   +1 more source

A Spectral Acceleration Approach for the Spherical Harmonics Discrete Ordinate Method

open access: yesRemote Sensing, 2020
A spectral acceleration approach for the spherical harmonics discrete ordinate method (SHDOM) is designed. This approach combines the correlated k-distribution method and some dimensionality reduction techniques applied on the optical parameters of an ...
Adrian Doicu   +2 more
doaj   +1 more source

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